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公开(公告)号：US11001638B2
公开(公告)日：2021-05-11
申请号：US15773821
申请日：2016-11-04
Applicant: Cancer Research Technology Limited
Inventor： Aymen Al-Shamkhani , Hak Tak Claude Chan , Mark Steven Cragg , Ruth Rosemary French , Martin John Glennie , Jane Elizabeth Willoughby
IPC: C07K16/28 , A61K39/395 , A61P35/02 , A61K39/00 , A61K45/06
Abstract: The invention relates to antibodies specific for 4-1BB and OX40, as well as to methods for using such antibodies and therapeutic uses thereof.
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公开(公告)号：US20180327504A1
公开(公告)日：2018-11-15
申请号：US15773821
申请日：2016-11-04
Applicant: Cancer Research Technology Limited
Inventor： Aymen Al-Shamkhani , Hak Tak Claude Chan , Mark Steven Cragg , Ruth Rosemary French , Martin John Glennie , Jane Elizabeth Willoughby
IPC: C07K16/28 , A61K39/00 , A61K45/06 , A61K39/395 , A61P35/02
CPC classification number: C07K16/2878 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/545 , A61K2039/57 , A61K2039/575 , A61K2039/80 , A61P35/02 , C07K16/2818 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/565 , C07K2317/567 , C07K2317/75
Abstract: The invention relates to antibodies specific for 4-1BB and OX40, as well as to methods for using such antibodies and therapeutic uses thereof.
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Patent Agency Ranking
公开(公告)号：US20220213207A9
公开(公告)日：2022-07-07
申请号：US17235174
申请日：2021-04-20
Applicant: Cancer Research Technology Limited
Inventor： Aymen Al-Shamkhani , Hak Tak Claude Chan , Mark Steven Cragg , Ruth Rosemary French , Martin John Glennie , Jane Elizabeth Willoughby
IPC: C07K16/28 , A61P35/02 , A61K39/00 , A61K39/395 , A61K45/06
Abstract: The invention relates to antibodies specific for 4-1BB and OX40, as well as to methods for using such antibodies and therapeutic uses thereof.
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公开(公告)号：US11780929B2
公开(公告)日：2023-10-10
申请号：US17235174
申请日：2021-04-20
Applicant: Cancer Research Technology Limited
Inventor： Aymen Al-Shamkhani , Hak Tak Claude Chan , Mark Steven Cragg , Ruth Rosemary French , Martin John Glennie , Jane Elizabeth Willoughby
IPC: A61K39/395 , C07K16/28 , A61P35/02 , A61K39/00 , A61K45/06
CPC classification number: C07K16/2878 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61P35/02 , C07K16/2818 , A61K2039/505 , A61K2039/507 , A61K2039/545 , A61K2039/57 , A61K2039/575 , A61K2039/80 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/565 , C07K2317/567 , C07K2317/75
Abstract: The invention relates to antibodies specific for 4-1BB and OX40, as well as to methods for using such antibodies and therapeutic uses thereof.
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公开(公告)号：US11447549B2
公开(公告)日：2022-09-20
申请号：US16633740
申请日：2018-07-26
Inventor： Björn Frendéus , Linda Mårtensson , Monika Semmrich , Ingrid Teige , Stephen Beers , Aymen Al-Shamkhani , Juliet Gray , Martin Glennie
IPC: A61K39/395 , C07K16/28 , A61K39/00
Abstract: Described is the sequential administration of first a Treg depleting antibody molecule selected from antibody molecules, such as an antibody molecule binding specifically to target belonging to the tumour necrosis factor receptor superfamily (TNFRSF), such as a Treg depleting anti-4-1 BB antibody or a Treg depleting OX-40 antibody, and then an immunostimulatory antibody molecule, such as an immunostimulatory anti-4-1 BB anti-body or an immunostimulatory OX-40 antibody, for use in the treatment of cancer. Described are also novel anti-4-1 BB antibodies and novel OX-40 antibodies that may be used in such sequential administration.
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公开(公告)号：US20210317222A1
公开(公告)日：2021-10-14
申请号：US17235174
申请日：2021-04-20
Applicant: Cancer Research Technology Limited
Inventor： Aymen Al-Shamkhani , Hak Tak Claude Chan , Mark Steven Cragg , Ruth Rosemary French , Martin John Glennie , Jane Elizabeth Willoughby
IPC: C07K16/28 , A61P35/02 , A61K39/00 , A61K39/395 , A61K45/06
Abstract: The invention relates to antibodies specific for 4-1BB and OX40, as well as to methods for using such antibodies and therapeutic uses thereof.
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公开(公告)号：US20200017594A9
公开(公告)日：2020-01-16
申请号：US15773821
申请日：2016-11-04
Applicant: Cancer Research Technology Limited
Inventor： Aymen Al-Shamkhani , Hak Tak Claude Chan , Mark Steven Cragg , Ruth Rosemary French , Martin John Glennie , Jane Elizabeth Willoughby
IPC: C07K16/28 , A61K39/00 , A61K45/06 , A61K39/395 , A61P35/02
Abstract: The invention relates to antibodies specific for 4-1BB and OX40, as well as to methods for using such antibodies and therapeutic uses thereof.
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