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公开(公告)号:US4978673A
公开(公告)日:1990-12-18
申请号:US172799
申请日:1988-03-28
申请人: Carlo Meroni , Stefano Maiorana , Mario Brufani , Massimo Pomponi , Riccardo Bernardi , Pier L. Rugarli , Pier G. Pagella
发明人: Carlo Meroni , Stefano Maiorana , Mario Brufani , Massimo Pomponi , Riccardo Bernardi , Pier L. Rugarli , Pier G. Pagella
IPC分类号: A61K31/40 , A61P21/00 , A61P25/02 , C07C57/145 , C07C59/255 , C07C59/265 , C07D487/04
CPC分类号: C07D487/04 , C07C57/145 , C07C59/255 , C07C59/265
摘要: Organic salts of physostigmine derivatives, having the following general mula: ##STR1## in which R is a linear or branched C.sub.2 -C.sub.12 alkyl or a cycloalkyl or an aryl, and X.sub.- is the anion of an organic acid, the process for their preparation and their pharmaceutical use for acetylcholinesterase inhibition purposes.