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公开(公告)号:US20210100805A1
公开(公告)日:2021-04-08
申请号:US16880871
申请日:2020-05-21
发明人: Vivek Saroj Kumar Chopra , Jorge DiMartino , Laurie A. Kenvin , Robert Douglas Knight , Kyle MacBerth , Krishnan Viswanadhan , Qiang Xu , Samuel V. Agresta
IPC分类号: A61K31/53 , A61K31/7068 , A61P35/02
摘要: Provided are methods and compositions for treating cancers in patients carrying an IDH2 mutation using a combination of an inhibitor of a mutant IDH2 enzyme and a DNA demethylating agent.