公开(公告)号：US20220160787A1

公开(公告)日：2022-05-26

申请号：US17439671

申请日：2020-03-16

申请人： Celularity Inc.

发明人： QIAN YE ,  Joseph GLEASON ,  Lin KANG ,  Robert J. HARIRI ,  Shuyang HE ,  Xiaokui ZHANG ,  Valentina ROUSSEVA

IPC分类号： A61K35/50

摘要： The present invention provides an isolated non-human placenta derived stem cell, wherein the stem cell expresses CD90 or wherein the stem cell expresses CD29. The present invention also provides a composition comprising an isolated non-human placenta derived stem cell of the invention or a population of isolated non-human placenta derived stem cells of the invention, and a carrier. The present invention also provides a composition of the invention for use in the manufacture of a medicament to reduce the incidence of rejection in a patient receiving a xenotransplant form a non-human donor. The present invention provides a method of treating a subject receiving a xenotransplant or xenotransfusion comprising the step of administering to the patient an effective amount of a non-human placenta derived stem cells.