公开(公告)号：US10683252B2

公开(公告)日：2020-06-16

申请号：US16474136

申请日：2017-12-15

申请人： Central Glass Company, Limited

发明人： Kenji Hosoi ,  Mineo Watanabe ,  Hideaki Imura ,  Kensuke Hirotaki ,  Naoya Ueshima

IPC分类号： C07C41/22 ,  C07C41/01 ,  C07C45/63

摘要： Fluoral is obtained by gas-phase fluorination of chloral in the presence of a catalyst and then reacted with trimethyl orthoformate, thereby readily forming 1,2,2,2-tetrafluoroethyl methyl ether as an intermediate for production of desflurane. 1,2,2,2-Tetrafluoroethyl difluoromethyl ether (desflurane) is produced with high yield from the thus-formed 1,2,2,2-tetrafluoroethyl methyl ether by chlorination and fluorination. This method enables efficient industrial-scale production of desflurane useful as an inhalation anesthetic.

公开(公告)号：US10882809B2

公开(公告)日：2021-01-05

申请号：US16474112

申请日：2017-12-15

申请人： Central Glass Company, Limited

发明人： Kenji Hosoi ,  Naoya Ueshima

IPC分类号： C07C41/22

摘要： A halogenated α-fluoroether of the formula (2) (where HaloR represents haloalkyl; R1 represents hydrogen, halogen, alkyl or substituted alkyl; and R2 represents alkyl or substituted alkyl) is produced efficiently on an industrial scale by reacting a halogenated aldehyde of the formula (1) (where HaloR represents haloalkyl) or an equivalent thereof with hydrogen fluoride.

公开(公告)号：US12098238B2

公开(公告)日：2024-09-24

申请号：US17800336

申请日：2021-02-24

申请人： Central Glass Company, Limited

发明人： Kensuke Hirotaki ,  Hirokatsu Nagura ,  Kenji Hosoi ,  Yukari Hara

IPC分类号： C08G59/06

CPC分类号： C08G59/06

摘要： A curable resin represented by General Formula (1). In General Formula (1), R1 each independently represent a monovalent substituent (an alkyl group, an alkoxy group, a fluorine atom, and the like), m is 0 to 4, n is 0 to 40, and R2's are each independently a monovalent group including a polymerizable functional group.