公开(公告)号：US20240150447A1

公开(公告)日：2024-05-09

申请号：US18501780

申请日：2023-11-03

Applicant: Cephalon, LLC

Inventor： Jason TIEN ,  Jennifer STRATTON ,  David S. WILSON

IPC: C07K16/18 ,  C07K16/28 ,  C12N9/24

CPC classification number: C07K16/18 ,  C07K16/2863 ,  C12N9/2402 ,  C12Y302/0105 ,  A61K2039/505 ,  C07K2317/52 ,  C07K2317/75 ,  C07K2317/77 ,  C07K2317/92 ,  C07K2319/30

Abstract: The present disclosure generally relates to compositions and methods for enhancing transport of molecules into the brain using modified IgG Fc regions, and methods of producing and using molecules comprising such modified Fc regions.