公开(公告)号：US20060252298A1

公开(公告)日：2006-11-09

申请号：US11410185

申请日：2006-04-24

申请人： Christopher Biddel ,  Winfried Kuhlmann ,  Colin Lanyi ,  Oscar-Werner Reif

发明人： Christopher Biddel ,  Winfried Kuhlmann ,  Colin Lanyi ,  Oscar-Werner Reif

IPC分类号： H01R11/20

CPC分类号： A61M39/16 ,  A61M39/18 ,  A61M2039/1027 ,  F16L37/26 ,  F16L2201/44

摘要： A connector system (10) for producing a sterile connection includes a fluid conduit (32), an engagement device (14, 22) designed to engage with a complementary engagement device (16, 24) of a complementary connector (12), a displacement device (26) with a substantially plane displacement surface (30) and a fluid conduit aperture (60) which extends through the displacement surface (30) and is connected to the fluid conduit (32), with the displacement device (26) being designed to displace the connector (12) and the complementary connector (12) relative to one another in a displacement direction (40) after the engagement device (14, 22) has engaged with the complementary engagement device (16, 24), and with the displacement direction (40) being substantially parallel to the displacement surface (30), and a sterile cover device (20, 74) designed to cover at least the fluid conduit aperture (60) in a sterile manner. The invention also relates to a method of use of the connector system (10) and of the complementary connector (12) for sterile connection of a fluid inlet of the connector (10) to a fluid outlet of the complementary connector.

摘要翻译： 用于产生无菌连接的连接器系统（10）包括流体导管（32），设计成与互补连接器（12）的互补接合装置（16,24）接合的接合装置（14,22） 具有基本平面位移表面（30）的装置（26）和延伸穿过位移表面（30）并且连接到流体导管（32）的流体导管孔（60），位移装置（26）被设计 在所述接合装置（14,22）已经与所述互补接合装置（16,24）接合之后，使所述连接器（12）和所述互补连接器（12）相对于彼此在位移方向（40）上移位，并且 位移方向（40）基本上平行于位移表面（30），以及设计成以无菌方式至少覆盖流体导管孔（60）的无菌盖装置（20,74）。 本发明还涉及使用连接器系统（10）和互补连接器（12）的方法，用于将连接器（10）的流体入口与互补连接器的流体出口无菌连接。

公开(公告)号：US06312591B1

公开(公告)日：2001-11-06

申请号：US09150790

申请日：1998-09-10

申请人： Vincenzo Vassarotti ,  Colin Lanyi ,  Christopher Biddell

发明人： Vincenzo Vassarotti ,  Colin Lanyi ,  Christopher Biddell

IPC分类号： B01D6120

CPC分类号： B01D65/08 ,  B01D61/18 ,  B01D61/20 ,  B01D61/22 ,  B01D63/08 ,  B01D63/082 ,  B01D63/087 ,  B01D2313/086 ,  B01D2321/2016 ,  B01D2321/2083 ,  G01N2001/4016

摘要： A filtration cell for carrying out a tangential flow filtration of a sample liquid contains at least two blocks and at least two filtration elements arranged between each pair of two adjacent blocks. The filtration elements each include an outlet for filtrate, a sheet of support material and two generally flat ultrafiltration or microfiltration membranes, arranged on either side of the support material in a sandwich construction. Each of the blocks, at a side adjacent the membranes, is provided with a respective channel for feeding a flow of sample liquid tangentially over the membranes such that each channel is connected in parallel with the inlet for the flow of sample liquid to be filtered and with an outlet for a concentrated solution. Each channel includes in its longitudinal direction a number of subsequent channel sections separated by transitional zones and is constructed and arranged such that the main flow direction in subsequent sections changes abruptly in the transitional zones.

摘要翻译： 用于进行样品液体的切向流过滤的过滤池包含至少两个块和至少两个布置在每对相邻块之间的过滤元件。 过滤元件各自包括用于滤液的出口，一片支撑材料和两个大致平坦的超滤或微滤膜，其布置在夹层结构中的支撑材料的两侧。 每个块在邻近膜的一侧上设置有相应的通道，用于在膜上切向地供给样品液体流，使得每个通道与待进行过滤的样品液体流的入口平行地连接， 配有浓缩溶液出口。 每个通道在其纵向方向上包括多个由过渡区隔开的后续通道部分，并且构造和布置成使得后续部分中的主流动方向在过渡区域中突然变化。