公开(公告)号：US10538545B2

公开(公告)日：2020-01-21

申请号：US15413428

申请日：2017-01-24

Applicant: Chung Yuan Christian University

Inventor： Tsai-Te Lu ,  Hsiao-Wen Huang ,  Chia-Her Lin ,  Yu-Ting Tseng ,  Wen-Feng Liaw ,  Hsi-Ya Huang ,  Show-Jen Chiou

IPC: C07F15/02 ,  A61K31/555

Abstract: Disclosed herein are novel compounds of formula (I) and (II), each of which may serve as a reagent to deliver nitric oxide (NO) and a therapeutic agent to treat NO-associated diseases. Also disclosed are a pharmaceutical composition comprising the compound of formula (I) or (II), a composite material comprising the compound of formula (I) or (II), and the uses thereof.