-
1.发明授权Liposome having inner water phase containing sulfobutyl ether cyclodextrin salt 有权脂质体内含水相，含有磺丁基醚环糊精盐公开(公告)号：US08871253B2
公开(公告)日：2014-10-28
申请号：US13502776
申请日：2010-10-26
申请人： Chunlei Li , Lan Zhang , Caixia Wang , Li Zhang , Dongmin Shen , Yanhui Li , Xian Xiu , Min Liang , Yongfeng Li
发明人： Chunlei Li , Lan Zhang , Caixia Wang , Li Zhang , Dongmin Shen , Yanhui Li , Xian Xiu , Min Liang , Yongfeng Li
IPC分类号： A61K9/127 , A61K31/475 , A61K31/4745 , A61P35/00 , B01J13/18 , A61K31/724 , A61K9/00 , A61K9/50 , A61K45/06 , A61K47/40
CPC分类号： A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/5089 , A61K31/4745 , A61K31/475 , A61K31/724 , A61K45/06 , A61K47/40 , A61K2300/00
摘要： A liposome comprising bilayer and inner water phase is disclosed. Said inner water phase contains sulfobutyl ether cyclodextrin and active compound. Said sulfobutyl ether cyclodextrin is sulfobutyl ether α-cyclodextrin, sulfobutyl ether β-cyclodextrin, or sulfobutyl ether γ-cyclodextrin.
摘要翻译： 公开了包含双层和内部水相的脂质体。 所述内水相含有磺丁基醚环糊精和活性化合物。 所述磺丁基醚环糊精是磺丁基醚α-环糊精，磺丁基醚和环糊精，或磺丁基醚γ-环糊精。
-
2.发明申请Liposome Having Inner Water Phase Containing Sulfobutyl Ether Cyclodextrin Salt 有权具有含有磺基丁基醚环糊精盐的内水相的脂质体公开(公告)号：US20120201874A1
公开(公告)日：2012-08-09
申请号：US13502776
申请日：2010-10-26
申请人： Chunlei Li , Lan Zhang , Caixia Wang , Li Zhang , Dongmin Shen , Yanhui Li , Xian Xiu , Min Liang , Yongfeng Li
发明人： Chunlei Li , Lan Zhang , Caixia Wang , Li Zhang , Dongmin Shen , Yanhui Li , Xian Xiu , Min Liang , Yongfeng Li
IPC分类号： A61K9/127 , B01J13/18 , A61P35/00 , A61K31/475 , A61K31/4745
CPC分类号： A61K9/127 , A61K9/0019 , A61K9/1271 , A61K9/5089 , A61K31/4745 , A61K31/475 , A61K31/724 , A61K45/06 , A61K47/40 , A61K2300/00
摘要： A liposome comprising bilayer and inner water phase is disclosed. Said inner water phase contains sulfobutyl ether cyclodextrin and active compound. Said sulfobutyl ether cyclodextrin is sulfobutyl ether α-cyclodextrin, sulfobutyl ether β-cyclodextrin, or sulfobutyl ether γ-cyclodextrin.
摘要翻译： 公开了包含双层和内部水相的脂质体。 所述内水相含有磺丁基醚环糊精和活性化合物。 所述磺丁基醚环糊精是磺丁基醚α-环糊精，磺丁基醚和环糊精，或磺丁基醚γ-环糊精。
-
3.发明申请公开(公告)号：US20110002977A1
公开(公告)日：2011-01-06
申请号：US12521357
申请日：2007-12-29
申请人： Chunlei Li , Jinxu Wang , Caixia Wang , Yanhui Li , Dongmin Shen , Wenmin Guo , Li Zhang , Lan Zhang
发明人： Chunlei Li , Jinxu Wang , Caixia Wang , Yanhui Li , Dongmin Shen , Wenmin Guo , Li Zhang , Lan Zhang
IPC分类号： A61K9/127 , A61K31/437 , A61K31/136 , A61P35/00
CPC分类号： A61K9/1273 , A61K9/1271 , A61K31/136 , A61K31/704
摘要： The present invention relates to a liposomal pharmaceutical preparation containing a multivalent ionic drug, a process for the preparation of the liposomal pharmaceutical preparation, and a use thereof in the treatment of diseases, in which the liposome has a size of about 30-80 nm, and the phospholipid bilayer has a phospholipid with a Tm higher than body temperature, so that the phase transition temperature of the liposome is higher than the body temperature.
摘要翻译： 本发明涉及含有多价离子药物的脂质体药物制剂，制备脂质体药物制剂的方法及其用于治疗脂质体具有约30-80nm尺寸的疾病的用途， 并且磷脂双层具有Tm高于体温的磷脂，使得脂质体的相变温度高于体温。
-
-
搜索结果
3 条记录 (耗时 0.023 秒)
