公开(公告)号：US20230233641A1

公开(公告)日：2023-07-27

申请号：US18093654

申请日：2023-01-05

Applicant: Colgate-Palmolive Company

Inventor： Bindu AIYAR ,  Purushottam JADHAV ,  Payal ARORA ,  Kshitij SATARDEKAR ,  Nikhil MALI

IPC: A61K36/61 ,  A61K9/00 ,  A61K36/54 ,  A61P29/00 ,  A61K45/06 ,  A61K47/10 ,  A61K36/9066

CPC classification number: A61K36/61 ,  A61K9/0053 ,  A61K36/54 ,  A61K36/9066 ,  A61K45/06 ,  A61K47/10 ,  A61P29/00 ,  A61K36/484

Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of herbal oils and extracts comprising (a) clove oil and/or eugenol (e.g., clove leaf oil and/or clove bud oil), (b) a cooling agent (e.g., menthol), (c) camphor, (d) an antimicrobial agent, e.g., turmeric and/or curcumin extract (e.g., turmeric, white turmeric (e.g., white curcumin) and (e) licorice; in an orally acceptable gel base, the gel base comprising one or more nonionic surfactants, the formulation providing a sustained release of the mixture of herbal oils and extracts following application to a tooth or gums; together with methods of making and using the same.