公开(公告)号：US20220340641A1

公开(公告)日：2022-10-27

申请号：US17413654

申请日：2019-12-06

申请人： CureVac AG

发明人： Amit AGGARWAL ,  Katja FIEDLER ,  Ulrike GNAD-VOGT ,  Regina HEIDENREICH ,  Mythili KONERU ,  Gregory D. PLOWMAN

IPC分类号： C07K14/74 ,  C07K14/705 ,  A61K47/18 ,  A61K47/24 ,  A61K47/28 ,  C12N15/62 ,  C12N9/14

摘要： The present invention provides an mRNA molecule encoding at least one KRAS variant peptide. Further, the invention provides a pharmaceutical composition and kit comprising the mRNA molecule. The mRNA molecule, pharmaceutical composition and kit are useful for treating cancer.