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公开(公告)号:US4554162A
公开(公告)日:1985-11-19
申请号:US607056
申请日:1984-05-04
申请人: Cynthia A. Young , John P. Schaumberg , Gerard C. Hokanson , James C. French , Josefino B. Tunac
发明人: Cynthia A. Young , John P. Schaumberg , Gerard C. Hokanson , James C. French , Josefino B. Tunac
摘要: A strain of actinomycete, NRRL 15758, is capable of producing the CL-1724 complex of compounds under conditions of aerobic fermentation in the presence of assimilable sources of carbon and nitrogen. The compound CL-1724B-2 exhibiting antimicrobial and antitumor activity, is claimed together with pharmaceutical compositions and methods of treating microbial infections and tumors in mammals employing these pharmaceutical compositions.
摘要翻译: 放线菌菌株NRRL 15758能够在需氧发酵的条件下在可同化的碳源和氮源的情况下生产化合物的CL-1724复合物。 表现出抗微生物和抗肿瘤活性的化合物CL-1724B-2与使用这些药物组合物的哺乳动物中治疗微生物感染和肿瘤的药物组合物和方法一起是要求的。