专利检索 ap:("Cynthia J. Burrows" OR "Arunkumar Kannan" OR "Peter A. Beal") AND inv:"Arunkumar Kannan" 第 1 页

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发明申请
METHODS AND COMPOSITIONS RELATED TO MODIFIED GUANINE BASES FOR CONTROLLING OFF-TARGET EFFECTS IN RNA INTERFERENCE 审中-公开
标题翻译：用于控制RNA干扰中的非目标效应的改性GUANINE基础相关方法和组合

公开(公告)号：US20120095077A1

公开(公告)日：2012-04-19

申请号：US13257093

申请日：2010-03-23

申请人： Cynthia J. Burrows , Arunkumar Kannan , Peter A. Beal

发明人： Cynthia J. Burrows , Arunkumar Kannan , Peter A. Beal

IPC分类号： A61K31/7088 , C07H19/167 , C07D473/18 , C07H21/02

CPC分类号： C07D487/04

摘要： Disclosed are compositions and methods related to modified nucleobases. Also disclosed are compositions and methods related to modified interfering RNAs. Also disclosed are compositions and methods related to modified guanine bases for controlling off-target effects in RNA interference.

摘要翻译： 公开了与修饰的核碱基相关的组合物和方法。还公开了与修饰的干扰RNA相关的组合物和方法。还公开了与用于控制RNA干扰中的脱靶作用的修饰的鸟嘌呤碱基相关的组合物和方法。