公开(公告)号：US20220336041A1

公开(公告)日：2022-10-20

申请号：US17636288

申请日：2020-09-08

Applicant: Cytiva Sweden AB

Inventor： Fredrik Edebratt ,  Olof Karlsson ,  Anna Lager ,  Jens Larsson

IPC: G16B15/00 ,  G01N33/68 ,  G16B40/20 ,  G16B45/00

Abstract: Disclosed is a method of qualifying a subgroup of target binding biomolecules from a larger group of target binding biomolecules for analysis. A competitive immunoassay including a target protein is used to identify 100 interactions between different pairs of the target binding biomolecules and interaction profiles are generated 200. Each target binding biomolecule is allocated 300 to a bin representing an epitope family and identified bins are associated in a circular or semi-circular bin chart on a display with identified respective target binding biomolecule(s). Based on the association 400 between identified bins and identified respective target binding molecule(s) in the bin chart, a subgroup of target binding biomolecules is selected 500 for further analysis by selecting one or more of the target binding biomolecule(s) of one or more of the bins.