公开(公告)号：US20200093941A1

公开(公告)日：2020-03-26

申请号：US16615958

申请日：2018-05-24

申请人： D.O.R.C. Dutch Ophthalmic Research Center (International) B.V.

发明人： Gerrit Reinold Jacob Melles

IPC分类号： A61K49/00 ,  A61F2/16 ,  A61F9/007

摘要： A staining composition is provided with improved staining intensity. The composition comprises a vital dye and hyaluronic acid, wherein the vital dye comprises Chicago Sky Blue and Trypan Blue. The staining composition is used to stain the lens capsule during cataract surgery and provides sufficient contrast such that no air bubble needs to be injected in the anterior chamber during cataract surgery.

公开(公告)号：US10426849B2

公开(公告)日：2019-10-01

申请号：US15422961

申请日：2017-02-02

申请人： D.O.R.C. Dutch Ophthalmic Research Center (International) B.V.

发明人： Gerrit Reinold Jacob Melles

IPC分类号： A61K49/00 ,  A61K9/00

摘要： The invention is directed to a staining composition and to the use of the staining composition in staining ocular tissue. In a first aspect, the invention provides a staining composition comprising a vital dye and a density increasing compound chosen from the group consisting of water soluble polymers and small inert molecules.