公开(公告)号：US20250073134A1

公开(公告)日：2025-03-06

申请号：US18725685

申请日：2023-05-25

Applicant: DAICEL CORPORATION

Inventor： Masaya OMURA ,  Mizuki UENO

IPC: A61K8/02 ,  A61K8/73 ,  A61K8/85

Abstract: Biodegradable spherical particles contain a biodegradable polymer as a main component. The biodegradable spherical particles have a particle size variation coefficient CV of 40% or less, and a biodegradation degree on the fifth day in a biodegradability test in accordance with OECD TG301F of 40% or less. A cosmetic composition contains the biodegradable spherical particles. A method for producing the biodegradable spherical particles includes preparing a mixture by mixing a biodegradable polymer, a plasticizer, and a water-soluble polymer; melt-kneading the mixture at 200° C. or higher and 280° C. or lower to yield a kneaded product; and removing the water-soluble polymer from the kneaded product.