专利检索 ap:("DAIICHI SANKYO COMPANY, LIMITED") AND inv:"Natsuki SAKURAI" 第 1 页

1.

发明公开
METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE 审中-公开

公开(公告)号：US20230382856A1

公开(公告)日：2023-11-30

申请号：US18249421

申请日：2021-10-29

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Natsuki SAKURAI , Tatsuhiro SAKAMOTO , Tomokazu OGURA

IPC分类号： C07D209/08 , C07D209/18 , C07D413/06

CPC分类号： C07D209/08 , C07D209/18 , C07D413/06

摘要： The present inventors found a novel method for reducing formyl groups with the use of a Lewis acid and a hydride reducing agent in a production method for a 3-methyl-4-haloindole derivative. The present inventors also found that demethylation and/or dehalogenation of the derivative are suppressed by this method, making post-treatment easier or the derivative obtained at a high yield.