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公开(公告)号：US09993297B2
公开(公告)日：2018-06-12
申请号：US14763514
申请日：2014-01-30
申请人： DIGMA MEDICAL LTD.
发明人： Ilan Ben-Oren , Avia Herschkovitz , Tamir Wolf , Irit Yaniv
CPC分类号： A61B18/24 , A61B2018/00202 , A61B2018/00273 , A61B2018/00434 , A61B2018/00494 , A61B2018/00577 , A61B2018/00773 , A61B2018/00982 , A61B2018/20359 , A61B2018/2272
摘要： The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.
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公开(公告)号：US10925671B2
公开(公告)日：2021-02-23
申请号：US16136530
申请日：2018-09-20
申请人： DIGMA MEDICAL LTD.
发明人： Ilan Ben-Oren , Avia Herschkovitz , Tamir Wolf , Irit Yaniv
摘要： The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.
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公开(公告)号：US11311337B2
公开(公告)日：2022-04-26
申请号：US16927104
申请日：2020-07-13
申请人： DIGMA MEDICAL LTD.
发明人： Ilan Ben-Oren , Avia Herschkovitz , Tamir Wolf , Irit Yaniv
摘要： The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.
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公开(公告)号：US10888377B2
公开(公告)日：2021-01-12
申请号：US15973053
申请日：2018-05-07
申请人： DIGMA MEDICAL LTD.
发明人： Ilan Ben-Oren , Avia Herschkovitz , Tamir Wolf , Irit Yaniv
摘要： The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.
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公开(公告)号：US10537387B2
公开(公告)日：2020-01-21
申请号：US15303080
申请日：2015-04-16
申请人： DIGMA MEDICAL LTD.
发明人： Ilan Ben Oren , Irit Yaniv , Tamir Wolf , Avia Herschkovitz
IPC分类号： A61B18/20 , A61B18/00 , A61B5/00 , A61B18/22 , A61B8/08 , A61B8/12 , A61B1/012 , A61B5/026 , A61B5/055 , A61B5/107
摘要： The present disclosure provides, according to some embodiments, methods and systems for selectively reducing, blocking or inhibiting at least part of the neural activity in an organ of a subject. In preferred embodiments, the method and system are used for selectively blocking at least part of the neural activity in a duodenum of a subject in need thereof. According to some embodiments, the selective blocking occurs through use of laser radiation. According to some embodiments, the selective blocking occurs through use of ultrasound energy. According to some embodiments, the selective blocking comprises causing damage to at least part of sensory nerves located within a target area while maintaining functional activity of tissue surrounding the sensory nerves by means of shielding it from the effects of laser radiation. According to some embodiments, the sensory nerves include neurons configured to transmit signals triggered by food passing through the duodenum, such as, but not limited to, neurohormonal signals.
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