公开(公告)号：US20140248662A1

公开(公告)日：2014-09-04

申请号：US14249587

申请日：2014-04-10

Applicant: DSM IP ASSETS B.V.

Inventor： Noël Nicolaas Maria Elisabeth VAN PEIJ ,  Herman Jan PEL ,  Thibaut Jose WENZEL ,  Adriana Marina RIEMENS ,  Ilse DE LANGE

IPC: C12P21/00 ,  C12N15/80

CPC classification number: C12P21/00 ,  A01K2267/01 ,  C12N9/2428 ,  C12N15/80 ,  C12N15/8509 ,  C12N15/902

Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.

Abstract translation: 本发明涉及用于生产感兴趣的化合物的重组宿主细胞。 本发明还涉及生产这种宿主细胞的方法。 本发明还涉及生产感兴趣的化合物。 本发明还涉及分离的多核苷酸和包含所述多核苷酸的载体和宿主细胞。

公开(公告)号：US20140099401A1

公开(公告)日：2014-04-10

申请号：US14075711

申请日：2013-11-08

Applicant: DSM IP ASSETS B.V.

Inventor： Jan Metske VAN DER LAAN ,  Mark Cristiaan STOR ,  Ilse DE LANGE ,  Lisette MOHRMANN

IPC: C12N9/82

CPC classification number: C12N9/82 ,  A23L5/25 ,  A23L29/06 ,  C12Y305/01001

Abstract: The present invention relates to newly identified asparaginase polypeptide variants of SEQ ID NO: 3 and to polynucleotide sequences that encode such novel asparaginase variants. Furthermore the invention relates to the use of these novel asparaginase variants in industrial processes.

Abstract translation: 本发明涉及新鉴定的SEQ ID NO：3的天冬酰胺酶多肽变体和编码这种新型天冬酰胺酶变体的多核苷酸序列。 此外，本发明涉及这些新型天冬酰胺酶变体在工业过程中的用途。