公开(公告)号：US09516893B2

公开(公告)日：2016-12-13

申请号：US14404878

申请日：2013-10-30

Applicant: DSM IP ASSETS B.V.

Inventor： Leigh Gibson ,  Regina Goralczyk ,  Hasan Mohajeri ,  Jonas Wittwer Schegg ,  Nicolle Goetz ,  Christina Kalarickal ,  Simone Koenig-Grillo ,  Marja Kanning ,  Damiet Josephina Petronella Cunera Koenders ,  Kathleen Simons

IPC: A23L1/30 ,  A23L1/305 ,  A23L2/66 ,  A61K9/00 ,  A61K38/47 ,  A61K47/12 ,  A61K38/00

CPC classification number: A23L33/175 ,  A23K20/147 ,  A23L2/66 ,  A23L33/18 ,  A23V2002/00 ,  A61K9/0095 ,  A61K38/00 ,  A61K38/47 ,  A61K47/12 ,  C12Y302/01017 ,  A23V2250/065

Abstract: This invention relates to a method of increasing a feeling of a) energy or b) cognitive functions, selected from the group consisting of: sustained attention, faster reaction times, and information processing; or c) quality of sleep; or d) feelings of well-being and happiness in a healthy adult using a dosage form comprising a low dose of a Trp-containing di- and/or tri-peptide mixture characterized in that the peptide composition is an egg iysozyme hydroiysate with a Trp/L!MAA ratio greater than 0.15 and which provides IQ-to 100 mg Trp per dose. This dosage form can be administered acutely or can be administered multiple times per day for an extended period of time.

Abstract translation: 本发明涉及增加a）能量或b）认知功能的感觉的方法，所述认知功能选自：持续关注，更快的反应时间和信息处理; 或c）睡眠质量; 或d）健康成年人使用包含低剂量含Trp的二 - 和/或三 - 肽混合物的剂型的健康和幸福的感觉，其特征在于肽组合物是具有Trp的蛋液质水合物 / L！MAA比大于0.15，并且每剂量提供IQ至100mg Trp。 该剂型可以急性施用，也可以每天长时间多次施用。