公开(公告)号：US20250073253A1

公开(公告)日：2025-03-06

申请号：US18949971

申请日：2024-11-15

Applicant: DSM IP Assets B.V.

Inventor： Britta BLOKKER ,  Stephane DUVAL ,  John Michael GEREMIA ,  Estefania PEREZ CALVO ,  Nathalie RICHARD ,  Jerome SCHMEISSER ,  Nicole SEIFERT ,  Viviane VERLHAC

IPC: A61K31/702 ,  A23K20/163 ,  A23K50/30 ,  A23K50/75 ,  A61K9/00 ,  A61P1/00

Abstract: Methods of feeding animals are disclosed whereby feed additives are provided that modulate the gut microbiome to prevent or treat dysfunctions in a gastrointestinal barrier. The present disclosure further relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to prevent or treat infections.

公开(公告)号：US20230004817A1

公开(公告)日：2023-01-05

申请号：US17779959

申请日：2020-11-23

Applicant: DSM IP Assets B.V.

Inventor： Ghislain SCHYNS ,  Britta BLOKKER ,  Joshua CLAYPOOL

IPC: G06N3/12 ,  G06T11/20 ,  G16B45/00

Abstract: A method for visualizing microbiome data is described. Respective microbes and/or genes in microbiome data stored In in a database are identified. A network comprising nodes interconnected by edges is generated in a memory of a computer, each node representing one or more identified microbes or one or more microbial metabolites, and each edge of the network representing an association between a respective pair of the one or more identified microbes or a reaction mediated between two metabolites by an enzyme encoded in the one or more identified genes, with at least some nodes and edges of the network being each associated with a condition attribute identifying a groups and/or a timestamp associated with a sample in the database. The displayed network is dynamically updated in accordance with a filtering of the microbiome data based on the condition attributed and/or the timestamp attributed. Corresponding systems and computer-readable storages are also described.

公开(公告)号：US20220000891A1

公开(公告)日：2022-01-06

申请号：US17291481

申请日：2019-11-08

Applicant: DSM IP Assets B.V. ,  Midori USA, Inc.

Inventor： Britta BLOKKER ,  Stephane DUVAL ,  John Michael GEREMIA ,  Estefania PEREZ CALVO ,  Nathalie RICHARD ,  Jerome SCHMEISSER ,  Nicole SEIFERT ,  Viviane VERLHAC

IPC: A61K31/702 ,  A61K9/00 ,  A61P1/00 ,  A23K20/163 ,  A23K50/75 ,  A23K50/30

Abstract: The present disclosure relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to prevent or treat dysfunctions in a gastrointestinal barrier. The present disclosure further relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to prevent or treat infections.