公开(公告)号：US20200087688A1

公开(公告)日：2020-03-19

申请号：US16471589

申请日：2017-12-14

Applicant: DSM IP Assets B.V.

Inventor： Marco Alexander VAN DEN BERG ,  Elaheh JAMALZADEH ,  Samuel Adrianus Maria RUINARD

IPC: C12P13/12 ,  A21D2/24 ,  A23L27/10 ,  C12P21/02

Abstract: The present invention relates to a method for the enzymatic reduction of cystine to cysteine comprising contacting cystine with a reduction solution comprising: (i) an active glutathione reductase (EC1.8.1.7); (ii) a cofactor; and (iii) glutathione; and recovering a cysteine comprising composition, wherein the reduction solution has a pH of at least 6 during contacting with cystine.

公开(公告)号：US20190330600A1

公开(公告)日：2019-10-31

申请号：US16472099

申请日：2017-12-14

Applicant: DSM IP Assets B.V.

Inventor： Marco Alexander VAN DEN BERG ,  Elaheh JAMALZADEH ,  Samuel Adrianus Maria RUINARD

IPC: C12N9/02

Abstract: The present invention relates to a polypeptide having glutathione reductase activity selected from the group consisting of: a) polypeptide having an amino acid sequence comprising the mature polypeptide sequence of SEQ ID NO: 1 or a 2) a polypeptide comprising an amino acid sequence that has at least 50% sequence identity with the mature polypeptide sequence of SEQ ID NO: 1.