公开(公告)号：US10052288B2

公开(公告)日：2018-08-21

申请号：US15641665

申请日：2017-07-05

Applicant: Da Volterra

Inventor： Francois Lescure ,  Jean De Gunzburg

IPC: A61K9/50 ,  A61K9/16 ,  A61K31/00 ,  A61K31/731 ,  A61K33/44

CPC classification number: A61K9/5073 ,  A61K9/1652 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5047 ,  A61K31/00 ,  A61K31/731 ,  A61K33/44 ,  A61K2300/00

Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.

公开(公告)号：US20170296478A1

公开(公告)日：2017-10-19

申请号：US15641665

申请日：2017-07-05

Applicant: Da Volterra

Inventor： Francois Lescure ,  Jean De Gunzburg

IPC: A61K9/50 ,  A61K31/731 ,  A61K31/00 ,  A61K33/44 ,  A61K9/16

CPC classification number: A61K9/5073 ,  A61K9/1652 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5047 ,  A61K31/00 ,  A61K31/731 ,  A61K33/44 ,  A61K2300/00

Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.

公开(公告)号：US11202761B2

公开(公告)日：2021-12-21

申请号：US16046501

申请日：2018-07-26

Applicant: Da Volterra

Inventor： Francois Lescure ,  Jean De Gunzburg

IPC: A61K9/50 ,  A61K33/44 ,  A61K31/731 ,  A61K31/00 ,  A61K9/16

Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.