-
公开(公告)号：US20200087321A1
公开(公告)日：2020-03-19
申请号：US16472109
申请日：2017-12-22
发明人： Shojiro Miyazaki , Masaharu Inui , Yasunobu Kurosaki , Yuko Yamamoto , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Masamichi Kishida
IPC分类号： C07D498/14
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US11046710B2
公开(公告)日：2021-06-29
申请号：US16472109
申请日：2017-12-22
发明人： Shojiro Miyazaki , Masaharu Inui , Yasunobu Kurosaki , Yuko Yamamoto , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Masamichi Kishida
IPC分类号： C07D498/14 , A61K31/553 , A61P17/00 , A61P19/00
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US11014939B2
公开(公告)日：2021-05-25
申请号：US16472109
申请日：2017-12-22
发明人： Shojiro Miyazaki , Masaharu Inui , Yasunobu Kurosaki , Yuko Yamamoto , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Masamichi Kishida
IPC分类号： C07D498/14 , A61K31/553 , A61P17/00 , A61P19/00
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I) or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US20180141960A1
公开(公告)日：2018-05-24
申请号：US15874768
申请日：2018-01-18
发明人： Shojiro Miyazaki , Yuko Yamamoto , Keisuke Suzuki , Masaharu Inui , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Taeko Shinozaki
IPC分类号： C07D498/10 , A61K9/20 , C07D498/04 , A61K31/553 , A61K9/48
CPC分类号： C07D498/10 , A61K9/20 , A61K9/48 , A61K31/553 , C07D498/04
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R7)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US09920068B2
公开(公告)日：2018-03-20
申请号：US15314887
申请日：2016-07-07
发明人： Shojiro Miyazaki , Yuko Yamamoto , Keisuke Suzuki , Masaharu Inui , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Taeko Shinozaki
IPC分类号： C07D498/04 , C07D498/10 , A61K9/20 , A61K9/48 , A61K31/553
CPC分类号： C07D498/10 , A61K9/20 , A61K9/48 , A61K31/553 , C07D498/04
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R7)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US10221195B2
公开(公告)日：2019-03-05
申请号：US15874768
申请日：2018-01-18
发明人： Shojiro Miyazaki , Yuko Yamamoto , Keisuke Suzuki , Masaharu Inui , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Taeko Shinozaki
IPC分类号： C07D498/10 , C07D498/04 , A61K9/20 , A61K9/48 , A61K31/553
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R7)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US09879032B2
公开(公告)日：2018-01-30
申请号：US15481151
申请日：2017-04-06
发明人： Shojiro Miyazaki , Yuko Yamamoto , Keisuke Suzuki , Masaharu Inui , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Taeko Shinozaki
IPC分类号： C07D498/10 , C07D498/04 , A61K9/20 , A61K9/48 , A61K31/553
CPC分类号： C07D498/10 , A61K9/20 , A61K9/48 , A61K31/553 , C07D498/04
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R7)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US20170240562A1
公开(公告)日：2017-08-24
申请号：US15314887
申请日：2016-07-07
发明人： Shojiro Miyazaki , Yuko Yamamoto , Keisuke Suzuki , Masaharu Inui , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Taeko Shinozaki
IPC分类号： C07D498/04
CPC分类号： C07D498/10 , A61K9/20 , A61K9/48 , A61K31/553 , C07D498/04
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R7)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.
-
公开(公告)号：US20170210755A1
公开(公告)日：2017-07-27
申请号：US15481151
申请日：2017-04-06
发明人： Shojiro Miyazaki , Yuko Yamamoto , Keisuki Suzuki , Masaharu Inui , Masanori Izumi , Kaori Soma , Anthony Pinkerton , Taeko Shinozaki
IPC分类号： C07D498/10 , A61K31/553 , A61K9/48 , C07D498/04 , A61K9/20
CPC分类号： C07D498/10 , A61K9/20 , A61K9/48 , A61K31/553 , C07D498/04
摘要： The present invention relates to a compound or a pharmacologically acceptable salt thereof having excellent tissue non-specific alkaline phosphatase inhibitory activity. The present invention provides a compound represented by the formula (I): wherein R1 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R2 and R3 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R4 and R5 are the same or different and each represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, R6 represents a hydrogen atom or the like, each R7 may be the same or different and may each represent an optionally substituted C1-6 alkoxy group or the like, X represents —CH═, —C(—R7)═, or —N═, and m represents 1 to 4, or a pharmacologically acceptable salt thereof.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.032 秒)
