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公开(公告)号:US20090215785A1
公开(公告)日:2009-08-27
申请号:US12378837
申请日:2009-02-20
申请人: Daisy Joe DuBois , Todd Richard Elworthy , Robert Than Hendricks , Johannes Cornelius Hermann , Raman K. Kondru , Yan Lou , Timothy D. Owens , David Bernard Smith
发明人: Daisy Joe DuBois , Todd Richard Elworthy , Robert Than Hendricks , Johannes Cornelius Hermann , Raman K. Kondru , Yan Lou , Timothy D. Owens , David Bernard Smith
IPC分类号: A61K31/4985 , C07D487/04 , A61P35/00
CPC分类号: C07D487/04
摘要: The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables Q and R are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
摘要翻译: 本发明涉及式I的新型吡咯并吡嗪衍生物的用途,其中变量Q和R如本文所述定义,其抑制JAK和SYK并且可用于治疗自身免疫和炎性疾病。