公开(公告)号：US20060014221A1

公开(公告)日：2006-01-19

申请号：US11040215

申请日：2005-01-21

申请人： Daniel O'Shannessy ,  Niranjan Sardesai ,  Jennifer Bones

发明人： Daniel O'Shannessy ,  Niranjan Sardesai ,  Jennifer Bones

IPC分类号： G01N33/53

CPC分类号： G01N33/57407 ,  G01N33/57488 ,  G01N2333/52

摘要： The invention relates to methods and kits for assessing occurrence in patient urine of peptides having amino acid sequences related to those of mesothelin, megakaryocyte potentiating factor, and other peptides that have been associated with occurrence in the serum of mesothelioma patients. The methods and kits can be used to diagnose mesothelioma in a patient, to predict development of mesothelioma in an otherwise asymptomatic patient, or to assess the efficacy of a mesothelioma therapeutic method.

摘要翻译： 本发明涉及用于评估患者尿中具有与间皮素，巨核细胞增强因子以及与间皮瘤患者的血清中发生相关的其它肽相关的氨基酸序列的肽的发生的方法和试剂盒。 方法和试剂盒可用于诊断患者的间皮瘤，以预测其他无症状患者的间皮瘤的发展，或评估间皮瘤治疗方法的功效。