专利检索 ap:("Daniela Eberts" OR "Martina Fatho" OR "Volker Lennerz" OR "Chris Schmidt" OR "Pierre Van Der Bruggen" OR "Catherine Wolfel" OR "Thomas Wolfel") AND inv:"Daniela Eberts" 第 1 页

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发明申请
Melanoma-associated MHC class I associated oligopeptides and the uses thereof 审中-公开
标题翻译：黑素瘤相关的MHC I类相关寡肽及其用途

公开(公告)号：US20090104186A1

公开(公告)日：2009-04-23

申请号：US11991339

申请日：2006-08-31

申请人： Daniela Eberts , Martina Fatho , Volker Lennerz , Chris Schmidt , Pierre Van Der Bruggen , Catherine Wolfel , Thomas Wolfel

发明人： Daniela Eberts , Martina Fatho , Volker Lennerz , Chris Schmidt , Pierre Van Der Bruggen , Catherine Wolfel , Thomas Wolfel

IPC分类号： A61K39/395 , C07K16/18 , C07H21/04 , A61K39/39 , A61P35/00 , C12N15/64 , C12N1/00

CPC分类号： A61K39/0011 , A61K38/1774 , A61K2039/57 , A61K2039/572 , A61K2039/585 , C07K14/4748 , C07K16/3053

摘要： The present invention relates to certain melanoma-associated oligopeptides that are recognized by CD8-positive cytotoxic T-lymphocytes (CTLs) as peptide antigen and which elicit a CTL-induced lysis and/or apoptosis of tumor cells. The present invention also relates to the use of these melanoma-associated oligopeptides in cancer therapy.

摘要翻译： 本发明涉及由CD8阳性细胞毒性T淋巴细胞（CTLs）识别为肽抗原并引起CTL诱导的肿瘤细胞裂解和/或凋亡的某些黑素瘤相关寡肽。本发明还涉及这些黑素瘤相关寡肽在癌症治疗中的用途。