公开(公告)号：US20060141461A1

公开(公告)日：2006-06-29

申请号：US10531964

申请日：2005-12-07

Applicant: David Keefe

Inventor： David Keefe

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  A61B17/435 ,  C12Q1/68 ,  C12Q1/6827 ,  C12Q1/6841 ,  C12Q1/6888 ,  C12Q2600/156 ,  C12Q2525/151

Abstract: The invention features a method of identifying oocytes with a risk of reproductive failure and/or aneuploidy based on a telomere length assay.

Abstract translation: 本发明的特征在于鉴定了基于端粒长度测定法具有生殖障碍和/或非整倍体风险的卵母细胞的方法。

公开(公告)号：US06357645B1

公开(公告)日：2002-03-19

申请号：US09636074

申请日：2000-08-10

Applicant: David Keefe

Inventor： David Keefe

IPC: B60R1106

CPC classification number: B60R11/00 ,  B60D1/60

Abstract: A storage holster designed to securely contain and provide easy access to a release pull bar that is used for unlocking a fifth wheel assembly of a transport truck. The holster comprises an elongated rectangular plate with a carrier projecting from one side of the plate. The carrier receives and supports a release pull bar and has an open end which commences at a point midway along the longitudinal axis of the plate. The closed end of the carrier terminates at the distal end of the plate and is provided with one or more holes to permit drainage of grease or oil that may be coated on a pull bar following use thereof. A pin, inserted through a hole in both the carrier and plate, works in combination with a padlock to function as a security and safety device to prevent the pull bar from being removed without authorization, or from maneuvering out of position when the truck is in transit. Connected near the proximal end and on the same side of the plate is a narrow rectangular collar lined with a rubber grommet. The collar helps to stabilize the position of a release pull bar during storage and prevents it from vibrating in the holster during transit. The invention also provides a means with which to attach the holster to a support surface of the truck, generally in an upwardly angled orientation to permit insertion and retention of a pull bar.

Abstract translation: 一种储存皮套，设计用于安全地容纳和容易地接近用于解锁运输卡车的第五轮组件的释放拉杆。 皮套包括细长矩形板，其具有从板的一侧突出的载体。 托架接收和支撑释放拉杆，并且具有开口端，该开口端在板的纵向轴线的中途开始。 载体的封闭端终止在板的远端，并且设置有一个或多个孔，以允许在使用之后可以涂覆在拉杆上的润滑脂或油的排出。 通过托架和板中的孔插入的销与挂锁组合起作用，用作安全和安全装置，以防止拉杆未经授权被移除，或者当卡车处于不适当的位置时被操纵 过境 连接在板的近端和同一侧上的是具有橡胶垫圈的狭窄的矩形套环。 领子有助于在储存期间稳定释放拉杆的位置，并防止其在运输过程中在皮套中振动。 本发明还提供了一种用于将皮套附接到卡车的支撑表面的装置，通常以向上倾斜的方向，以允许拉杆的插入和保持。

公开(公告)号：US20090114144A1

公开(公告)日：2009-05-07

申请号：US12200370

申请日：2008-08-28

Applicant: David Keefe

Inventor： David Keefe

IPC: B42D9/00

CPC classification number: B42D9/005 ,  B42P2241/16 ,  B42P2241/18 ,  B43K23/001 ,  B43L1/00 ,  B43L1/004 ,  B43L1/008 ,  B43L1/04 ,  B43L21/00

Abstract: An interactive, novelty bookmark device includes a composite frame having a front and back cover, a magnetic drawing screen mounted within the composite frame, wherein a portion of the drawing screen is accessible through a window in the front cover for receipt and persistent display of information input by a user of the device, a stylus having a magnetic tip and configured for use by the user to input information onto the magnetic drawing screen, an erase lever slidably mounted within the composite frame and having a magnet disposed thereon to selectively erase the magnetic drawing screen, and an engagement appendage mounted to and extending from the frame for releasably securing the interactive bookmark device to associated printed reading material which needs to be bookmarked.

Abstract translation: 交互式，新颖的书签装置包括具有前盖和后盖的复合框架，安装在复合框架内的磁力绘图屏幕，其中绘图屏幕的一部分可通过前盖中的窗口接近并持续显示信息 由设备的用户输入，具有磁头并且被配置为供用户将信息输入到磁力绘图屏上的触控笔;可滑动地安装在复合框架内并具有设置在其上的磁体以选择性地擦除磁性的擦除杆 绘图屏幕和安装到框架上并从框架延伸的配合附件，用于将交互式书签设备可释放地固定到需要被加书签的相关联的打印阅读材料。

公开(公告)号：US20050176052A1

公开(公告)日：2005-08-11

申请号：US11070988

申请日：2005-03-03

Applicant: David Keefe

Inventor： David Keefe

IPC: C12N15/873 ,  G06T5/00 ,  G06T7/00 ,  C12Q1/68 ,  G01N33/48 ,  G01N33/50 ,  G06F19/00

CPC classification number: G06T7/0012 ,  C12N15/873 ,  G06T7/70 ,  G06T7/97 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30024

Abstract: The developmental potential of a mammalian oocyte for successful implantation is evaluated by producing a plurality of intensity images of the oocyte using polarized light optics, and calculating a retardance image with a sensitivity of 3 nm or less. The presence, location and morphological characteristics of a meiotic spindle in the oocyte can then be determined based on the spindle structure in the retardance image, and the developmental potential of the oocyte can be evaluated.

Abstract translation: 通过使用偏振光学光学器件产生卵母细胞的多个强度图像，并计算出具有3nm或更小的灵敏度的延迟图像来评估用于成功植入的哺乳动物卵母细胞的发育潜力。 然后可以基于延迟图像中的纺锤体结构确定卵母细胞中减数分裂纺锤体的存在，位置和形态特征，并且可以评估卵母细胞的发育潜力。