公开(公告)号：US5814524A

公开(公告)日：1998-09-29

申请号：US572005

申请日：1995-12-14

申请人： David R. Walt ,  Karri L Michael ,  Suneet Chadha

发明人： David R. Walt ,  Karri L Michael ,  Suneet Chadha

IPC分类号： G01N21/77 ,  G01N33/543 ,  G01N33/552

CPC分类号： G01N21/6452 ,  G01N21/6428 ,  G01N21/6456 ,  Y10S435/808 ,  Y10S436/80 ,  Y10S436/805

摘要： The present invention is an optical sensor apparatus for far-field viewing and imaging as well as for the optical detection and analytical measurement of at least one species of analyte in a remotely-positioned fluid sample. The apparatus employs an imaging fiber comprising a fiber optic array and a Gradient Index lens; and utilizes a remotely-positioned solid substrate having light energy absorbing indicator ligands on an external surface for reactive contact with individual species of analytes when present in a fluid sample. The optical sensor apparatus is able to view an object and provide an image of the object located at a pre-set optical distance remote from the imaging fiber. The apparatus is also able to detect and identify, qualitatively and quantitatively, one or more analytes of interest in a flowing solid, gaseous, or liquid sample at remote locations distanced from the imaging fiber itself.

摘要翻译： 本发明是用于远场观察和成像的光学传感器装置，以及用于远程定位的流体样品中的至少一种分析物的光学检测和分析测量。 该装置采用包括光纤阵列和渐变折射率透镜的成像光纤; 并且当存在于流体样品中时，利用在外表面上具有光能吸收指示剂配体的远程固定的固体基质用于与各种分析物的反应性接触。 光学传感器装置能够观察物体并提供位于远离成像光纤的预设光学距离处的物体的图像。 该设备还能够在远离成像纤维本身的远程位置处检测和鉴定在流动的固体，气体或液体样品中感兴趣的一种或多种感兴趣的分析物。