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公开(公告)号：US4468383A
公开(公告)日：1984-08-28
申请号：US427857
申请日：1982-09-29
申请人： David Rodbard , Y. Shimohigashi , Hao-Chia Chen , Tommaso Costa
发明人： David Rodbard , Y. Shimohigashi , Hao-Chia Chen , Tommaso Costa
IPC分类号： A61K38/00 , C07K14/70 , A61K37/00 , C07C103/52
CPC分类号： C07K14/702 , A61K38/00
摘要： The compounds of the invention are symmetrical dimers of enkephalin polypeptides comprising enkephalin polypeptide monomers linked at the C-termini thereof with a difunctional amino bridging group. The compounds are useful as investigative tools for probing the opiate receptor membranes, particularly as radiolabelled ligands for exploring the delta opiate receptor, and also have particular use as narcotic and/or analgesic agents.
摘要翻译： 本发明的化合物是脑啡肽多肽的对称二聚体，其包含在其C-末端与双官能氨基桥连基团连接的脑啡肽多肽单体。 这些化合物可用作探测阿片剂受体膜的研究工具，特别是用作探索δ阿片剂受体的放射性标记的配体，并且还可用作麻醉剂和/或止痛剂。
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公开(公告)号：US20080235053A1
公开(公告)日：2008-09-25
申请号：US11688768
申请日：2007-03-20
申请人： Pinaki Ray , Greg Matian , Aparna Srinivasan , Pamela Lai , David Rodbard , Roger Levine , Andrea Burling , Laura Robinson , David Price
发明人： Pinaki Ray , Greg Matian , Aparna Srinivasan , Pamela Lai , David Rodbard , Roger Levine , Andrea Burling , Laura Robinson , David Price
CPC分类号： G16H15/00 , A61B5/14532 , G06F19/3456 , G06Q50/24 , G16H10/60 , G16H40/63 , G16H50/20
摘要： A diabetes management system or process is provided herein that may be used to analyze and recognize patterns for a large amount of blood glucose concentration measurements and other physiological parameters related to the glycemia of a patient. In particular, a communication medium is provided. The communication medium includes first, second, third, fourth and fifth display areas. The second through fifth display areas can be disposed in the first display area. The second display area has identification information of a patient. The third display area has a plurality of textual messages indicative of glycemic status of the patient. The fourth display area includes a chart indicative of a variability of the glucose concentration of the patient over a predetermined time period. Other messages can also be provided to ensure compliance of any prescribed diabetes regiments or to guide the patient in managing the patient's diabetes.
摘要翻译： 本文提供的糖尿病管理系统或过程可用于分析和识别大量血糖浓度测量和与患者血糖相关的其它生理参数的模式。 特别地，提供通信介质。 通信介质包括第一，第二，第三，第四和第五显示区域。 第二至第五显示区域可以设置在第一显示区域中。 第二显示区域具有患者的识别信息。 第三显示区域具有指示患者血糖状态的多个文本消息。 第四显示区域包括指示在预定时间段内患者的葡萄糖浓度的变异性的图表。 还可以提供其他信息以确保任何规定的糖尿病团队的遵守或指导患者管理患者的糖尿病。
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公开(公告)号：US20080234992A1
公开(公告)日：2008-09-25
申请号：US11688639
申请日：2007-03-20
申请人： Pinaki RAY , Greg Matian , Aparna Srinivasan , David Rodbard , David Price
发明人： Pinaki RAY , Greg Matian , Aparna Srinivasan , David Rodbard , David Price
摘要： A diabetes management system or process is provided herein that may be used to analyze and recognize patterns for a large number of blood glucose concentration measurements and other physiological parameters related to the glycemia of a patient. In particular, a method of monitoring glycemia in a patient may include storing a patient's data on a suitable device, such as, for example, a blood glucose meter. The patient's data may include blood glucose concentration measurements. The diabetes management system or process may be installed on, but is not limited to, a personal computer, an insulin pen, an insulin pump, or a glucose meter. The diabetes management system or process may identify a plurality of pattern types from the data including a testing/dosing pattern, a hypoglycemic pattern, a hyperglycemic pattern, a blood glucose variability pattern, and a comparative pattern. After identifying a particular pattern with the data management system or process, a warning message may be displayed on a screen of a personal computer or a glucose meter. Other messages can also be provided to ensure compliance of any prescribed diabetes regiments or to guide the patient in managing the patient's diabetes.
摘要翻译： 本文提供了可用于分析和识别大量血糖浓度测量和与患者血糖相关的其它生理参数的模式的糖尿病管理系统或过程。 特别地，监测患者血糖的方法可包括将患者的数据存储在合适的装置上，例如血糖仪。 患者的数据可能包括血糖浓度测量。 糖尿病管理系统或过程可以安装在个人计算机，胰岛素笔，胰岛素泵或葡萄糖计量仪上，但不限于此。 糖尿病管理系统或过程可以从包括测试/给药模式，低血糖模式，高血糖模式，血糖变异性模式和比较模式的数据中识别多种模式类型。 在使用数据管理系统或处理识别特定模式之后，可以在个人计算机或葡萄糖计的屏幕上显示警告消息。 还可以提供其他信息以确保任何规定的糖尿病团队的遵守或指导患者管理患者的糖尿病。
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公开(公告)号：US08758245B2
公开(公告)日：2014-06-24
申请号：US11688639
申请日：2007-03-20
申请人： Pinaki Ray , Greg Matian , Aparna Srinivasan , David Rodbard , David Price
发明人： Pinaki Ray , Greg Matian , Aparna Srinivasan , David Rodbard , David Price
IPC分类号： A61B5/00
摘要： A diabetes management system or process is provided herein that may be used to analyze and recognize patterns for a large number of blood glucose concentration measurements and other physiological parameters related to the glycemia of a patient. In particular, a method of monitoring glycemia in a patient may include storing a patient's data on a suitable device, such as, for example, a blood glucose meter. The patient's data may include blood glucose concentration measurements. The diabetes management system or process may be installed on, but is not limited to, a personal computer, an insulin pen, an insulin pump, or a glucose meter. The diabetes management system or process may identify a plurality of pattern types from the data including a testing/dosing pattern, a hypoglycemic pattern, a hyperglycemic pattern, a blood glucose variability pattern, and a comparative pattern. After identifying a particular pattern with the data management system or process, a warning message may be displayed on a screen of a personal computer or a glucose meter. Other messages can also be provided to ensure compliance of any prescribed diabetes regiments or to guide the patient in managing the patient's diabetes.
摘要翻译： 本文提供了可用于分析和识别大量血糖浓度测量和与患者血糖相关的其它生理参数的模式的糖尿病管理系统或过程。 特别地，监测患者血糖的方法可包括将患者的数据存储在合适的装置上，例如血糖仪。 患者的数据可能包括血糖浓度测量。 糖尿病管理系统或过程可以安装在个人计算机，胰岛素笔，胰岛素泵或葡萄糖计量仪上，但不限于此。 糖尿病管理系统或过程可以从包括测试/给药模式，低血糖模式，高血糖模式，血糖变异性模式和比较模式的数据中识别多种模式类型。 在使用数据管理系统或处理识别特定模式之后，可以在个人计算机或葡萄糖计的屏幕上显示警告消息。 还可以提供其他信息以确保任何规定的糖尿病团队的遵守或指导患者管理患者的糖尿病。
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公开(公告)号：US20080234943A1
公开(公告)日：2008-09-25
申请号：US11688743
申请日：2007-03-20
申请人： Pinaki RAY , Greg Matian , Aparna Srinivasan , David Rodbard , David Price
发明人： Pinaki RAY , Greg Matian , Aparna Srinivasan , David Rodbard , David Price
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/7275 , A61B5/7435 , G01N35/00871 , G06F19/3456 , G16H15/00 , G16H50/20
摘要： A diabetes management system or process is provided herein that may be used to analyze and recognize patterns for a large amount of blood glucose concentration measurements and other physiological parameters related to the glycemia of a patient. In particular, a method of monitoring glycemia in a patient may include storing a patient's data on a suitable device, such as, for example, a glucose meter. The patient's data may include blood glucose concentration measurements. The diabetes management system or process may be installed on, but is not limited to, a personal computer, an insulin pen, an insulin pump, or a glucose meter. The diabetes management system or process may identify a plurality of pattern types from the data including a testing/dosing pattern, a hypoglycemic pattern, a hyperglycemic pattern, a variability pattern, and a comparative pattern. After identifying a particular pattern with the data management system or process, a warning message may be displayed on a screen of a personal computer or a glucose meter. Other messages can also be provided to ensure compliance of any prescribed diabetes regiments or to guide the patient in managing the patient's diabetes.
摘要翻译： 本文提供的糖尿病管理系统或过程可用于分析和识别大量血糖浓度测量和与患者血糖相关的其它生理参数的模式。 特别地，监测患者血糖的方法可包括将患者的数据存储在合适的装置上，例如葡萄糖计。 患者的数据可能包括血糖浓度测量。 糖尿病管理系统或过程可以安装在个人计算机，胰岛素笔，胰岛素泵或葡萄糖计量仪上，但不限于此。 糖尿病管理系统或过程可以从包括测试/给药模式，低血糖模式，高血糖模式，变异性模式和比较模式的数据中识别多种模式类型。 在使用数据管理系统或处理识别特定模式之后，可以在个人计算机或葡萄糖计的屏幕上显示警告消息。 还可以提供其他信息以确保任何规定的糖尿病团队的遵守或指导患者管理患者的糖尿病。
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