公开(公告)号：US20250069705A1

公开(公告)日：2025-02-27

申请号：US18940983

申请日：2024-11-08

Applicant: DeepMind Technologies Limited

Inventor： Andrew W. Senior ,  James Kirkpatrick ,  Laurent Sifre ,  RIchard Andrew Evans ,  Hugo Penedones ,  Chongli Qin ,  Ruoxi Sun ,  Karen Simonyan ,  John Jumper

IPC: G16B40/20 ,  G06F18/2413 ,  G06N3/044 ,  G06N3/045 ,  G06N3/047 ,  G06N3/08 ,  G06N20/00 ,  G16B15/20 ,  G16H10/40

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing protein structure prediction and protein domain segmentation. In one aspect, a method comprises generating a plurality of predicted structures of a protein, wherein generating a predicted structure of the protein comprises: updating initial values of a plurality of structure parameters of the protein, comprising, at each of a plurality of update iterations: determining a gradient of a quality score for the current values of the structure parameters with respect to the current values of the structure parameters; and updating the current values of the structure parameters using the gradient.