公开(公告)号：US20040186060A1

公开(公告)日：2004-09-23

申请号：US10740946

申请日：2003-12-18

Applicant: Dendreon Corporation

Inventor： David F. Duncan ,  L. Josue Alfaro-Lopez ,  Mallareddy Komandla ,  Odile Esther Levy ,  Ofir Moreno ,  Joseph E. Semple ,  Amir P. Tamiz

IPC: A61K038/04 ,  A61K031/16 ,  A61K031/18

CPC classification number: C07D231/56 ,  C07D333/38

Abstract: The present invention provides matriptase inhibitors and compositions thereof useful for treating cancer. Martripase is a trypsin-like serine protease active in the development of cancerous conditions, such as tumors and metastasis of cancer.

Abstract translation: 本发明提供了可用于治疗癌症的基质酶抑制剂及其组合物。 枸杞子是一种胰蛋白酶样的丝氨酸蛋白酶，可在肿瘤和肿瘤转移等癌症病症中起积极作用。