专利检索 ap:("Denis Paul Harkin" OR "Vitali Proutski" OR "Julie Clarke" OR "Peter Kerr" OR "Richard Kennedy" OR "Andreas Winter" OR "Timothy Davison" OR "Max Bylesjo" OR "Vadim Farztdinov" OR "Claire Trinder" OR "Robert James Holt") AND inv:"Julie Clarke" 第 1 页

1.

发明授权
Colon cancer gene expression signatures and methods of use 有权

公开(公告)号：US10196691B2

公开(公告)日：2019-02-05

申请号：US13981601

申请日：2012-01-25

申请人： Denis Paul Harkin , Vitali Proutski , Julie Clarke , Peter Kerr , Richard Kennedy , Andreas Winter , Timothy Davison , Max Bylesjo , Vadim Farztdinov , Claire Trinder , Robert James Holt

发明人： Denis Paul Harkin , Vitali Proutski , Julie Clarke , Peter Kerr , Richard Kennedy , Andreas Winter , Timothy Davison , Max Bylesjo , Vadim Farztdinov , Claire Trinder , Robert James Holt

IPC分类号： C12Q1/6886

摘要： A gene expression signature of colon cancer, microarrays including them and methods of using the colon gene expression signature are provided. The gene expression signature is especially useful for determining the prognosis of a patient diagnosed with colon cancer, such as stage II colon cancer. The gene signature described herein is also useful for determining effectiveness of surgical resection with or without adjuvant chemotherapy, and determining possibility of cancer recurrence in patients with colon cancer.