公开(公告)号：US20240335433A1

公开(公告)日：2024-10-10

申请号：US18627617

申请日：2024-04-05

申请人： Dennis W. Stacey

发明人： Dennis W. Stacey

IPC分类号： A61K31/4375 ,  A61K9/00 ,  A61P35/00

CPC分类号： A61K31/4375 ,  A61K9/0019 ,  A61P35/00

摘要： A normal cell cycle synchronization process includes repeated administration of a drug specifically toxic for a single cell cycle phase to selectively synchronize normal cells. The selective synchronization of normal cells allows for the selective targeting of abnormal cells with cell cycle phase specific toxins. Such selective targeting may be useful in the treatment of a number of medical conditions.

公开(公告)号：US20210275562A1

公开(公告)日：2021-09-09

申请号：US17249528

申请日：2021-03-04

申请人： Dennis W. Stacey

发明人： Dennis W. Stacey

IPC分类号： A61K31/7072 ,  A61K9/00 ,  A61K31/475

摘要： A cancer treatment method includes administering a first dose of a drug selectively targeting cells in a particular phase (e.g., S phase cells); and administering an additional dose of the drug after waiting a full normal cell cycle. The method takes advantage of the uniformity of cell cycle length in normal cells (e.g., normal small intestine cells) and the and the lack of this uniformity, or variation in cell cycle length of cancer cells.