公开(公告)号：US20220071519A1

公开(公告)日：2022-03-10

申请号：US17291158

申请日：2019-11-06

Applicant: DexCom, Inc.

Inventor： Giovanni SPARACINO ,  Nunzio CAMERLINGO ,  Martina VETTORETTI ,  Andrea FACCHINETTI ,  Simone DEL FAVERO ,  Giacomo CAPPON

IPC: A61B5/145 ,  A61B5/00

Abstract: Mitigation of the risk of prolonged hypoglycemia in T1D management requires patient to assume a small dose of fast-acting carbohydrates, called hypotreatment (HT), as soon as hypoglycemia is detected. This invention consists in a method that, on the basis of the datastream generated by a continuous glucose monitoring (CGM) sensor, triggers the assumption of preventive HTs i.e., snacks that, being quickly absorbed into the circulation, avoid, or at least mitigate, a forthcoming hypoglycemic event. The method resorts to the “dynamic risk” (DR) non-linear function, which combines current glycemia with its rate-of-change provided by CGM, adapted to distinguish the severity of the about-to-happen hypoglycemia. The method has been tested in a simulated realistic scenario. Results show that the administration of an HT in advance, as triggered by the new method, brings to a strong reduction of the time that a patient would have spent in hypoglycemia assuming the HT at hypoglycemic threshold crossing.

公开(公告)号：US20240197260A1

公开(公告)日：2024-06-20

申请号：US18068400

申请日：2022-12-19

Applicant: Dexcom, Inc.

Inventor： Nunzio CAMERLINGO ,  Ilaria SIVIERO ,  Martina VETTORETTI ,  Simone DEL FAVERO ,  Giovanni SPARACINO ,  Andrea FACCHINETTI

IPC: A61B5/00

CPC classification number: A61B5/7203 ,  A61B5/0004 ,  A61B5/725 ,  A61B5/14532

Abstract: Certain aspects of the present disclosure relate to methods and systems for noise reduction in analyte data. Raw analyte data is input into a partitioning algorithm to generate partitioned data. An adaptive filter generates rough filtered partitions reducing a noise component in each partition of the partitioned data. A smoothing algorithm smooths the rough filtered partitions to generate smooth filtered data with reduced noise.