-
![3-(1,2,3-Triazol-4-yl) pyrrolo [2,3-b] pyridine derivatives](/abs-image/US/2012/03/01/US20120053178A1/abs.jpg.150x150.jpg)
1.发明申请公开(公告)号：US20120053178A1
公开(公告)日：2012-03-01
申请号：US13318518
申请日：2010-04-08
IPC分类号： A61K31/437 , A61P37/00 , A61P35/00 , A61P35/04 , C07D471/04 , A61K31/5377
CPC分类号： C07D471/04
摘要： Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim (1), are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumours.
摘要翻译： 其中R1，R2和R3具有权利要求（1）所示含义的式（I）化合物是PDK1的抑制剂和细胞增殖/细胞活力，可用于治疗肿瘤。
-
![7-(1,2,3-TRIAZOL-4-YL) PYRROLO [2,3-B] PYRAZINE DERIVATIVES](/abs-image/US/2013/08/22/US20130217951A1/abs.jpg.150x150.jpg)
2.发明申请公开(公告)号：US20130217951A1
公开(公告)日：2013-08-22
申请号：US13882872
申请日：2011-10-12
IPC分类号： C07D487/04 , A61K45/06 , A61K31/4985
CPC分类号： C07D487/04 , A61K31/4985 , A61K45/06
摘要： Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in Claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumours.
摘要翻译： 其中R1，R2和R3具有权利要求1所述含义的式（I）化合物是PDK1的抑制剂和细胞增殖/细胞活力，可用于治疗肿瘤。
-
![5 (1,2,3-TRIAZOL-4-YL)-7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES](/abs-image/US/2013/10/31/US20130289017A1/abs.jpg.150x150.jpg)
3.发明申请5 (1,2,3-TRIAZOL-4-YL)-7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES 有权5（1,2,3-三唑-4-基）-7H-吡咯并[2,3-D]吡啶衍生物公开(公告)号：US20130289017A1
公开(公告)日：2013-10-31
申请号：US13978545
申请日：2011-12-15
IPC分类号： C07D487/04 , A61K45/06 , A61K31/519
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D487/02
摘要： Compounds of the formula (I), in which R1, R2, R2a and R3 have the meanings indicated in Claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumours.
摘要翻译： 其中R1，R2，R2a和R3具有权利要求1所述含义的式（I）化合物是PDK1的抑制剂和细胞增殖/细胞活力，可用于治疗肿瘤。
-
4.发明申请6-(PYRROLOPYRIDINYL) PYRIMIDIN-2-YLAMINE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF CANCER AND AIDS. 有权6-（吡咯并吡啶基）吡咯烷-2-酮衍生物及其用于治疗癌症和AIDS的用途。公开(公告)号：US20110082140A1
公开(公告)日：2011-04-07
申请号：US12664791
申请日：2008-05-23
申请人： Dieter Dorsch , Margarita Wucherer-Plietker , Lars Thore Burgdorf , Christian Sirrenberg , Christina Esdar , Thomas J.J. Mueller , Eugen Merkul
发明人： Dieter Dorsch , Margarita Wucherer-Plietker , Lars Thore Burgdorf , Christian Sirrenberg , Christina Esdar , Thomas J.J. Mueller , Eugen Merkul
IPC分类号： A61K31/506 , C07D471/04 , A61K31/496 , A61K31/5377 , A61P35/00 , A61P35/02
CPC分类号： C07D471/04
摘要： Compounds of the formula (I), in which R1, R2, R3 and R4 have the meanings indicated in claim (1), are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumours.
摘要翻译： 其中R1，R2，R3和R4具有权利要求（1）所示含义的式（I）化合物是细胞增殖/细胞活力的抑制剂，可用于治疗肿瘤。
-
5.发明授权6-(pyrrolopyridinyl) pyrimidin-2-ylamine derivatives and the use thereof for the treatment of cancer and AIDS 有权6-（吡咯并吡啶基）嘧啶-2-基胺衍生物及其用于治疗癌症和AIDS的用途公开(公告)号：US08546390B2
公开(公告)日：2013-10-01
申请号：US12664791
申请日：2008-05-23
申请人： Dieter Dorsch , Margarita Wucherer-Plietker , Lars T. Burgdorf , Christian Sirrenberg , Christina Esdar , Thomas J. J. Mueller , Eugen Merkul
发明人： Dieter Dorsch , Margarita Wucherer-Plietker , Lars T. Burgdorf , Christian Sirrenberg , Christina Esdar , Thomas J. J. Mueller , Eugen Merkul
IPC分类号： C07D471/04 , A61K31/437
CPC分类号： C07D471/04
摘要： Compounds of the formula (I), in which R1, R2, R3 and R4 have the meanings indicated in claim (1), are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumors.
摘要翻译： 其中R1，R2，R3和R4具有权利要求（1）所示含义的式（I）化合物是细胞增殖/细胞活力的抑制剂，可用于治疗肿瘤。
-
![3-(1,2,3-triazol-4-yl) pyrrolo [2,3-b] pyridine derivatives](/abs-image/US/2013/09/24/US08541584B2/abs.jpg.150x150.jpg)
6.发明授权公开(公告)号：US08541584B2
公开(公告)日：2013-09-24
申请号：US13318518
申请日：2010-04-08
IPC分类号： C07D471/02 , A61K31/44 , A61K31/535
CPC分类号： C07D471/04
摘要： Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in claim (1), are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.
摘要翻译： 其中R1，R2和R3具有权利要求（1）所示含义的式（I）化合物是PDK1的抑制剂和细胞增殖/细胞活力，可用于治疗肿瘤。
-
![5-(1,2,3-triazol-4-yl)-7H-pyrrolo[2,3-D]pyrimidine derivatives](/abs-image/US/2015/07/14/US09079910B2/abs.jpg.150x150.jpg)
7.发明授权5-(1,2,3-triazol-4-yl)-7H-pyrrolo[2,3-D]pyrimidine derivatives 有权5-（1,2,3-三唑-4-基）-7H-吡咯并[2,3-D]嘧啶衍生物公开(公告)号：US09079910B2
公开(公告)日：2015-07-14
申请号：US13978545
申请日：2011-12-15
IPC分类号： C07D487/04 , C07D487/02 , A61K31/519 , A61K45/06
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D487/02
摘要： Compounds of the formula (I), in which R1, R2, R2a and R3 have the meanings indicated in Claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.
摘要翻译： 其中R1，R2，R2a和R3具有权利要求1所述含义的式（I）化合物是PDK1的抑制剂和细胞增殖/细胞活力，可用于治疗肿瘤。
-
![Substituted 7-(1,2,3-Triazol-4-yl)-pyrrolo[2,3-b]pyrazines](/abs-image/US/2014/10/21/US08865715B2/abs.jpg.150x150.jpg)
8.发明授权公开(公告)号：US08865715B2
公开(公告)日：2014-10-21
申请号：US13882872
申请日：2011-10-12
IPC分类号： A61K31/4985 , C07D487/04 , A61K45/06
CPC分类号： C07D487/04 , A61K31/4985 , A61K45/06
摘要： The invention relates to compounds the formula (I): and pharmaceutically usable salts, tautomers and stereoisomers thereof, wherein R1, R2 and R3 are defined herein. The compounds of formula (I) and their pharmaceutically usable salts, tautomers and stereoisomers are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.
摘要翻译： 本发明涉及式（I）化合物及其药学上可用的盐，互变异构体和立体异构体，其中R 1，R 2和R 3在本文中定义。 式（I）化合物及其药学上可用的盐，互变异构体和立体异构体是PDK1的抑制剂和细胞增殖/细胞活力，可用于治疗肿瘤。
-
公开(公告)号：US20130310391A1
公开(公告)日：2013-11-21
申请号：US13983083
申请日：2012-01-09
申请人： Dieter Dorsch , Christian Sirrenberg , Thomas J.J. Mueller , Eugen Merkul , Gnuni Amatunu Karapetyan
发明人： Dieter Dorsch , Christian Sirrenberg , Thomas J.J. Mueller , Eugen Merkul , Gnuni Amatunu Karapetyan
IPC分类号： C07D471/04 , C07D519/00
CPC分类号： C07D471/04 , A61K31/437 , A61K31/4375 , A61K45/06 , C07D519/00 , A61K2300/00
摘要： Compounds of the formula (I) in which R, R1, R2 and R3 have the meanings indicated in Claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumours.
-
![4 (PYRROLO[2,3-C]PYRIDINE-3-YL)PYRIMIDIN-2-AMINE DERIVATIVES](/abs-image/US/2010/11/18/US20100292262A1/abs.jpg.150x150.jpg)
10.发明申请公开(公告)号：US20100292262A1
公开(公告)日：2010-11-18
申请号：US12863817
申请日：2008-12-23
IPC分类号： A61K31/506 , C07D471/04 , A61P31/12 , A61P35/04 , A61P35/02
CPC分类号： C07D471/04
摘要： Compounds of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumours.
摘要翻译： 其中R1，R2，R3，R4和R5具有权利要求1所述含义的式（I）化合物是细胞增殖/细胞活力的抑制剂，可用于治疗肿瘤。
-
-
-
-
-
-
-
-
-
搜索结果
191 条记录 (耗时 0.027 秒)
