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公开(公告)号：US20090215673A1
公开(公告)日：2009-08-27
申请号：US12272554
申请日：2008-11-17
IPC分类号： A61K38/14
摘要： Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
摘要翻译： 公开了纯化被一个或多个各自包含一个或多个可用作抗菌剂的膦酰基的取代基取代的糖肽的方法。 所述方法包括使糖肽衍生物的溶液与含聚苯乙烯的树脂接触，用水溶液洗脱树脂，并分离纯化的糖肽衍生物。
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公开(公告)号：US20110257364A1
公开(公告)日：2011-10-20
申请号：US12947686
申请日：2010-11-16
IPC分类号： C07K1/16
摘要： Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
摘要翻译： 公开了纯化被一个或多个各自包含一个或多个可用作抗菌剂的膦酰基的取代基取代的糖肽的方法。 所述方法包括使糖肽衍生物的溶液与含聚苯乙烯的树脂接触，用水溶液洗脱树脂，并分离纯化的糖肽衍生物。
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公开(公告)号：US07858583B2
公开(公告)日：2010-12-28
申请号：US12272554
申请日：2008-11-17
IPC分类号： A61K38/14
摘要： Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
摘要翻译： 公开了纯化被一个或多个各自包含一个或多个可用作抗菌剂的膦酰基的取代基取代的糖肽的方法。 所述方法包括使糖肽衍生物的溶液与含聚苯乙烯的树脂接触，用水溶液洗脱树脂，并分离纯化的糖肽衍生物。
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公开(公告)号：US07468420B2
公开(公告)日：2008-12-23
申请号：US11977605
申请日：2007-10-25
IPC分类号： C07K14/00
摘要： Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
摘要翻译： 公开了纯化被一个或多个各自包含一个或多个可用作抗菌剂的膦酰基的取代基取代的糖肽的方法。 所述方法包括使糖肽衍生物的溶液与含聚苯乙烯的树脂接触，用水溶液洗脱树脂，并分离纯化的糖肽衍生物。
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公开(公告)号：US07375181B2
公开(公告)日：2008-05-20
申请号：US11301740
申请日：2005-12-13
IPC分类号： C07K7/60
摘要： Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
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公开(公告)号：US07015307B2
公开(公告)日：2006-03-21
申请号：US10226676
申请日：2002-08-23
IPC分类号： A61K38/04
摘要： Disclosed are methods of purifying glycopeptides that are substituted with one or more substituents each comprising one or more phosphono groups that are useful as antibacterial agents. The methods include contacting a solution of the glycopeptide derivatives with a polystyrene-containing resin, eluting the resin with an aqueous solution, and isolating the purified glycopeptide derivative.
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