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公开(公告)号：US07686798B2
公开(公告)日：2010-03-30
申请号：US12419943
申请日：2009-04-07
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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公开(公告)号：US07544192B2
公开(公告)日：2009-06-09
申请号：US10800162
申请日：2004-03-12
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
摘要翻译： 本发明提供用于治疗鼻窦炎的可生物降解植入物。 可生物降解的植入物具有尺寸，形状，密度，粘度和/或粘膜粘附性，防止在预期治疗期间鼻窦的粘膜纤毛内衬基本上被清除。 可生物降解的植入物包括持续释放治疗剂，例如抗生素，甾族抗炎药或两者。 可生物降解的植入物可以采取各种形式，例如棒，丸，珠，条或微粒，并且可以递送到各种药学上可接受的载体中的窦内。
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公开(公告)号：US07713255B2
公开(公告)日：2010-05-11
申请号：US12419930
申请日：2009-04-07
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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公开(公告)号：US07662141B2
公开(公告)日：2010-02-16
申请号：US12419925
申请日：2009-04-07
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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公开(公告)号：US08109918B2
公开(公告)日：2012-02-07
申请号：US12479794
申请日：2009-06-06
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
摘要翻译： 本发明提供用于治疗鼻窦炎的可生物降解植入物。 可生物降解的植入物具有尺寸，形状，密度，粘度和/或粘膜粘附性，防止在预期治疗期间鼻窦的粘膜纤毛内衬基本上被其清除。 可生物降解的植入物包括持续释放治疗剂，例如抗生素，甾族抗炎药或两者。 可生物降解的植入物可以采取各种形式，例如棒，丸，珠，条或微粒，并且可以递送到各种药学上可接受的载体中的窦内。
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公开(公告)号：US07691094B2
公开(公告)日：2010-04-06
申请号：US12419937
申请日：2009-04-07
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
摘要翻译： 本发明提供用于治疗鼻窦炎的可生物降解植入物。 可生物降解的植入物具有尺寸，形状，密度，粘度和/或粘膜粘附性，防止在预期治疗期间鼻窦的粘膜纤毛内衬基本上被其清除。 可生物降解的植入物包括持续释放治疗剂，例如抗生素，甾族抗炎药或两者。 可生物降解的植入物可以采取各种形式，例如棒，丸，珠，条或微粒，并且可以递送到各种药学上可接受的载体中的窦内。
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公开(公告)号：US07662142B2
公开(公告)日：2010-02-16
申请号：US12419927
申请日：2009-04-07
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M31/00
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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公开(公告)号：US20090192488A1
公开(公告)日：2009-07-30
申请号：US12419925
申请日：2009-04-07
申请人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
发明人： Donald J. Eaton , Mary L. Moran , Rodney Brenneman
IPC分类号： A61M5/31
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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公开(公告)号：US07951135B2
公开(公告)日：2011-05-31
申请号：US12883090
申请日：2010-09-15
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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公开(公告)号：US07951131B2
公开(公告)日：2011-05-31
申请号：US12883079
申请日：2010-09-15
CPC分类号： A61M31/007 , A61K9/0024 , A61K9/0043 , A61K31/43 , A61K31/573 , A61K31/58 , A61K47/34
摘要： The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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