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公开(公告)号:US20110224174A1
公开(公告)日:2011-09-15
申请号:US12723003
申请日:2010-03-12
申请人: Donald W. Miller , Samuel C. Augustine , Jon C. Wagner , Thomas L. McDonald , Dennis H. Robinson
发明人: Donald W. Miller , Samuel C. Augustine , Jon C. Wagner , Thomas L. McDonald , Dennis H. Robinson
摘要: The present invention provides a creatine ester anti-inflammatory compound which may be received by animals and then metabolized into a biologically active form of creatine. The biologically active creatine inhibits the production of chemical mediators, released during an inflammatory response, which are important components in the inflammatory response and the inflammation and pain resulting from physical or chemical trauma to cells and tissue.
摘要翻译: 本发明提供肌酸酯抗炎化合物,其可以被动物接受,然后代谢成生物活性形式的肌酸。 生物活性肌酸抑制在炎症反应期间释放的化学介质的产生,其是炎症反应中的重要组成部分以及由对细胞和组织的物理或化学创伤引起的炎症和疼痛。
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公开(公告)号:US20090137669A1
公开(公告)日:2009-05-28
申请号:US11955681
申请日:2007-12-13
申请人: Donald W. Miller , Samuel C. Augustine , Jon C. Wagner , Thomas L. McDonald , Dennis H. Robinson
发明人: Donald W. Miller , Samuel C. Augustine , Jon C. Wagner , Thomas L. McDonald , Dennis H. Robinson
IPC分类号: A61K31/221 , C07C229/10 , A61P29/00
CPC分类号: A61K31/221 , A23K20/142 , A23K40/10 , A23K50/10 , A23K50/40 , A23L33/175 , A61K31/198 , A61K31/22 , A61K31/661
摘要: The present invention provides a creatine ester anti-inflammatory compound which may be received by animals and then metabolized into a biologically active form of creatine. The biologically active creatine inhibits the production of chemical mediators, released during an inflammatory response, which are important components in the inflammatory response and the inflammation and pain resulting from physical or chemical trauma to cells and tissue.
摘要翻译: 本发明提供肌酸酯抗炎化合物,其可以被动物接受,然后代谢成生物活性形式的肌酸。 生物活性肌酸抑制在炎症反应期间释放的化学介质的产生,其是炎症反应中的重要组成部分以及由对细胞和组织的物理或化学创伤引起的炎症和疼痛。
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公开(公告)号:US09833427B2
公开(公告)日:2017-12-05
申请号:US12723003
申请日:2010-03-12
申请人: Donald W. Miller , Samuel C. Augustine , Jon C. Wagner , Thomas L. McDonald , Dennis H. Robinson
发明人: Donald W. Miller , Samuel C. Augustine , Jon C. Wagner , Thomas L. McDonald , Dennis H. Robinson
摘要: The present invention provides a creatine ester anti-inflammatory compound which may be received by animals and then metabolized into a biologically active form of creatine. The biologically active creatine inhibits the production of chemical mediators, released during an inflammatory response, which are important components in the inflammatory response and the inflammation and pain resulting from physical or chemical trauma to cells and tissue.
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公开(公告)号:US07988447B2
公开(公告)日:2011-08-02
申请号:US11926555
申请日:2007-10-29
CPC分类号: F28F9/026 , F23L15/00 , F28D9/0031 , F28F3/025 , F28F2250/104 , Y02E20/348
摘要: A formed sheet heat exchanger is provided for exchanging heat between fluids is provided. The apparatus includes flow divider sheets that are positioned in a stacked configuration and extend in a longitudinal direction so that adjacent pairs of the sheets define flow passages therebetween for receiving first and second fluids. Each of the sheets is nonuniform in the longitudinal direction, having a manifold portion and a corrugated portion. The corrugated portions of each adjacent pair of sheets define a plurality of fluid channels therebetween that are connected to the portion of the flow passage defined between the manifold portions. The fluid channels are configured to receive the first or second fluids and transfer thermal energy therebetween through the flow divider sheets.
摘要翻译: 提供了用于在流体之间交换热量的成形片式热交换器。 该装置包括分层片,该分流片位于堆叠构型中并沿纵向方向延伸,使得相邻的一对片在其间限定了用于接收第一和第二流体的流动通道。 每个片材在纵向方向上不均匀,具有歧管部分和波纹部分。 每个相邻的一对片的波纹部分在其间限定多个流体通道,其连接到限定在歧管部分之间的流动通道的部分。 流体通道被配置为接收第一或第二流体并且通过分流片传递其间的热能。
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