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![Salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and crystal form thereof](/abs-image/US/2021/01/19/US10894768B2/abs.jpg.150x150.jpg)
公开(公告)号：US10894768B2
公开(公告)日：2021-01-19
申请号：US16328492
申请日：2016-08-26
申请人： Dong-A St Co., Ltd.
发明人： Woo Young Kwak , Chang-Yong Shin , Punna Reddy Ullapu , Sun-Ho Choi , Min-Jung Lee , Ji-Su Kim
IPC分类号： C07D207/09 , A61K31/40 , C07D207/08
摘要： The present invention relates to a novel salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and a crystal form thereof. Also, the novel salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and the crystal form thereof according to examples of the present invention have remarkably excellent stability, hygroscopicity and solubility.
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![NOVEL SALT OF (R)-(1-METHYLPYRROLIDINE-3-YL)METHYL(3'-CHLORO-4'-FLUORO-[1,1'-BIPHENYL]-2-YL)CARBAMATE AND CRYSTAL FORM THEREOF](/abs-image/US/2019/06/27/US20190194129A1/abs.jpg.150x150.jpg)
2.发明申请公开(公告)号：US20190194129A1
公开(公告)日：2019-06-27
申请号：US16328492
申请日：2016-08-26
申请人： Dong-A St Co., Ltd.
发明人： Woo Young Kwak , Chang-Yong Shin , Punna Reddy Ullapu , Sun-Ho Choi , Min-Jung Lee , Ji-Su Kim
IPC分类号： C07D207/09
CPC分类号： C07D207/09 , A61K31/40 , C07B2200/13 , C07D207/06
摘要： The present invention relates to a novel salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and a crystal form thereof. Also, the novel salt of (R)-(1-methylpyrrolidine-3-yl)methyl(3′-chloro-4′-fluoro-[1,1′-biphenyl]-2-yl)carbamate and the crystal form thereof according to examples of the present invention have remarkably excellent stability, hygroscopicity and solubility.
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