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公开(公告)号:US20220098245A1
公开(公告)日:2022-03-31
申请号:US17346245
申请日:2021-06-13
Applicant: Dr. Subhajit Dasgupta
Inventor: Subhajit Dasgupta
IPC: C07K14/165
Abstract: The multi-epitope SARS-COV2 Spike peptides are analyzed for their ability to form association or binding complex with HLA-DR1 and human TLR8 by using computer modeling and molecular docking experiments. These peptides are identified as candidates for vaccine development as well as antibody-based immunotherapy.
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公开(公告)号:US20230250136A1
公开(公告)日:2023-08-10
申请号:US17736755
申请日:2022-05-04
Applicant: Dr. Subhajit Dasgupta
Inventor: Subhajit Dasgupta
IPC: C07K14/165 , A61P31/14
CPC classification number: C07K14/165 , A61P31/14
Abstract: The identified peptide sequences form moderate to strong heterodimeric complexes with SARS-COV2 (B.1.617.2) virus Spike envelope proteins and a range of virus nonstructural protein sequences NSP1-14. These identified peptides are proposed to use in antiviral immunotherapy and supportive combination with chemical compound(s) for chemotherapy. The sequence ID of the identified peptides are, Seq1: ISD1, Seq2: ISD2, Seq3: ISD3, Seq4: ISD4, Seq5: ISD5, Seq6: ISD6, Seq7 Ip2, Seq8: Ip1, Seq9: Ip3, Seq10: Ip5, Seq11: Ip7, Seq12: Ip8, Seq13: Ip9, Seq14: SOI1, Seq15: SOI2, Seq16: SOI5, Seq17: SOI7, Seq18: SOI9, Seq19: SO10, Seq20: SO11.
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