公开(公告)号：US20230203202A1

公开(公告)日：2023-06-29

申请号：US18062453

申请日：2022-12-06

Applicant: Dragonfly Therapeutics, Inc.

Inventor： Mitchell Bigelow ,  Mark DeRose ,  Jinyan Du ,  Robin Friedman ,  Pyae P. Hein ,  Stuart William Hicks ,  Zong Sean Juo ,  Xinbi Li ,  Christopher Ryan Morgan

IPC: C07K16/46 ,  A61P35/04

CPC classification number: C07K16/468 ,  A61P35/04 ,  C07K2317/565 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/53 ,  C07K2317/31

Abstract: Multispecific binding proteins that bind NKG2D receptor, CD16, and 5T4 are described, as well as pharmaceutical compositions, formulations, and therapeutic methods of the multispecific binding proteins useful for the treatment of cancer.