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公开(公告)号：US10883870B2
公开(公告)日：2021-01-05
申请号：US16674053
申请日：2019-11-05
Applicant: Drexel University
Abstract: The fiber optic probe detects changes in ultrasound pressure in an immersion medium such as a liquid, a gas, or a solid, where the system includes an optical fiber probe having a fiber of the probe has a highly doped (or regular) core with a diameter in the range 5 to 10 μm and a clad diameter equal to or more than 50 μm; and the optical fiber tip has been modified in a D-shaped (or V-shaped) structure where the clad material has been removed from one side of the cylindrical fiber to the surface of the fiber core; then, this modified region of the fiber is coated, with a very thin layer of a metallic material, ranging from 3 to 10 nm.
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Patent Agency Ranking
公开(公告)号：US20170199076A1
公开(公告)日：2017-07-13
申请号：US15477247
申请日：2017-04-03
Applicant: Drexel University
CPC classification number: G01H9/004 , A61B8/4281 , A61B2562/0247 , A61B2562/0266 , G01L11/025 , G01L11/04 , G02B6/241 , G02B6/262
Abstract: A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound waves up to 100 MHz, for imaging of micro structures and more. For applications up to 100 MHz, without spatial averaging corrections, the probe tip is modified by reducing the fiber diameter to 7 um or less. Also, to maximize acousto-optic interaction, the probe tip, not just its end face, may be coated with a thin layer of metallic material. This thin film coating satisfies partial transparency of the metallic coating. The coating thickness may range from 2 nm to 10 nm or others depending on the type of the coating material. The probe detects the pressure of acoustic and/or ultrasound waves propagating within an immersion medium, whenever the probe tip is immersed inside the medium, and having a reasonable immersion contact surface.
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公开(公告)号：US20210052874A1
公开(公告)日：2021-02-25
申请号：US17072435
申请日：2020-10-16
Applicant: DREXEL UNIVERSITY
Inventor： Peter A. Lewin , Elizabeth S. S. Papazoglou , Youhan Sunny , Chris R. Bawiec , Leonid Zubkov , An Nguyen , Joshua Samuels
Abstract: The present invention is directed to an ultrasound device for use in implementing therapeutic treatments and transdermal analyte delivery. The device includes a piezoelectric transducer that efficiently and safely converts electrical energy to ultrasonic waves, and has a unique structure including a piezoelectric element positioned between two opposing, flexible concave covers. The device may be used for various therapeutic purposes including wound healing, tissue stimulation and transdermal analyte delivery. The invention is further directed to a novel analyte delivery system including the ultrasound device and an encapsulated analyte.
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公开(公告)号：US20140133280A1
公开(公告)日：2014-05-15
申请号：US14159649
申请日：2014-01-21
Applicant: Drexel University
Inventor： Afshin S. Daryoush , Peter A. Lewin , Rupa Gopinath Minasamudram , Mahmoud El-Sherif
IPC: G01H9/00
Abstract: Disclosed is detecting changes in pressure in a medium, with an optical fiber having a core diameter at an immersion surface contact of the fiber of less than 10 μm; a layer of material deposited on said end of the fiber, the material being of a thickness of from about 2 nm to about 10 nm. Also disclosed is detecting pressure waves in a medium comprising: contacting the medium with a fiber optic, the fiber integrated with a light source and a detector, the fiber optic having a diameter of less than 10 μm at an immersion surface contact of the fiber; providing a thin layer of material on the immersion surface contact, wherein said thin layer of material is of a thickness in a range of from about 2 nm to about 10 nm; and detecting Fresnel back reflections from the immersion end of the fiber.
Abstract translation: 本发明公开了一种介质中的压力变化，纤维的芯径在纤维的浸入面接触小于10μm的光纤; 沉积在纤维的所述端部上的材料层，该材料的厚度为约2nm至约10nm。 还公开了检测介质中的压力波，其包括：使介质与光纤接合，所述光纤与光源和检测器集成，所述光纤在纤维的浸没表面接触处具有小于10μm的直径; 在浸没表面接触处提供薄层材料，其中所述薄层材料的厚度在约2nm至约10nm的范围内; 并从纤维的浸入端检测菲涅尔反射反射。
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公开(公告)号：US20200080887A1
公开(公告)日：2020-03-12
申请号：US16674053
申请日：2019-11-05
Applicant: Drexel University
IPC: G01H9/00
Abstract: The fiber optic probe detects changes in ultrasound pressure in an immersion medium such as a liquid, a gas, or a solid, where the system includes an optical fiber probe having a fiber of the probe has a highly doped (or regular) core with a diameter in the range 5 to 10 μm and a clad diameter equal to or more than 50 μm; and the optical fiber tip has been modified in a D-shaped (or V-shaped) structure where the clad material has been removed from one side of the cylindrical fiber to the surface of the fiber core; then, this modified region of the fiber is coated, with a very thin layer of a metallic material, ranging from 3 to 10 nm.
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公开(公告)号：US10466096B2
公开(公告)日：2019-11-05
申请号：US15477247
申请日：2017-04-03
Applicant: Drexel University
Abstract: A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound waves up to 100 MHz, for imaging of micro structures and more. For applications up to 100 MHz, without spatial averaging corrections, the probe tip is modified by reducing the fiber diameter to 7 um or less. Also, to maximize acousto-optic interaction, the probe tip, not just its end face, may be coated with a thin layer of metallic material. This thin film coating satisfies partial transparency of the metallic coating. The coating thickness may range from 2 nm to 10 nm or others depending on the type of the coating material. The probe detects the pressure of acoustic and/or ultrasound waves propagating within an immersion medium, whenever the probe tip is immersed inside the medium, and having a reasonable immersion contact surface.
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