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公开(公告)号：US20180208593A1
公开(公告)日：2018-07-26
申请号：US15875069
申请日：2018-01-19
发明人： Andrew Payne , Jose Luis Castro Pineiro , Louise Michelle Birch , Afzal Khan , Alan James Braunton , James Edward Kitulagoda , Motohiro Soejima
IPC分类号： C07D471/04 , C07D401/04
CPC分类号： C07D471/04 , C07D401/04
摘要： 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.
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公开(公告)号：US20160244445A1
公开(公告)日：2016-08-25
申请号：US15025996
申请日：2014-09-30
发明人： Andrew Payne , Jose Luis Castro Pineiro , Louise Michelle Birch , Afzal Khan , Alan James Braunton , James Edward Kitulagoda , Motohiro Soejima
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D401/04
摘要： 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.
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公开(公告)号：US10072005B2
公开(公告)日：2018-09-11
申请号：US15875069
申请日：2018-01-19
发明人： Andrew Payne , Jose Luis Castro Pineiro , Louise Michelle Birch , Afzal Khan , Alan James Braunton , James Edward Kitulagoda , Motohiro Soejima
IPC分类号： C07D471/04 , A61K31/437 , C07D401/04
CPC分类号： C07D471/04 , C07D401/04
摘要： 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.
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公开(公告)号：US09926312B2
公开(公告)日：2018-03-27
申请号：US15025996
申请日：2014-09-30
发明人： Andrew Payne , Jose Luis Castro Pineiro , Louise Michelle Birch , Afzal Khan , Alan James Braunton , James Edward Kitulagoda , Motohiro Soejima
IPC分类号： C07D471/04 , A61K31/437 , C07D401/04
CPC分类号： C07D471/04 , C07D401/04
摘要： 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.
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公开(公告)号：US20150094328A1
公开(公告)日：2015-04-02
申请号：US14501355
申请日：2014-09-30
发明人： Andrew Payne , Jose Luis Castro Pineiro , Louise Michelle Birch , Afzal Khan , Alan James Braunton , James Edward Kitulagoda , Motohiro Soejima
IPC分类号： C07D401/04
CPC分类号： C07D471/04 , C07D401/04
摘要： 4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.
摘要翻译： 作为毒蕈碱乙酰胆碱受体（mAChR）M1的调节剂的4-氮杂吲哚衍生物，其可用于预防或疾病改善或对症治疗与神经系统疾病如阿尔茨海默氏型痴呆（AD）或路易体痴呆相关的认知缺陷 （DLB）和包含4-氮杂吲哚衍生物作为活性成分的药物组合物。
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