公开(公告)号：US20150064081A1

公开(公告)日：2015-03-05

申请号：US14514853

申请日：2014-10-15

Applicant: EMD Millipore Corporation

Inventor： Christopher A. Scott ,  Brian Foley

IPC: B01L3/00

CPC classification number: B01L3/50255 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/0678 ,  B01L2200/0684 ,  B01L2200/141 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/0858

Abstract: A multi-well assembly including a filter plate and receiver plate. Each plate includes a plurality of wells, which, when the filter plate is placed in nesting relationship with the receiver plate, each filter plate well has a corresponding receiver plate well into which it extends. The receiver plate wells are of a non-uniform cross-section in order to increase the gap between the outer walls of the filter plate wells and the inner walls of a corresponding receiver plate well when the receiver plate and filter plate are in nesting relationship. The increased gap size reduces wicking and cross-contamination. A multi-section well of maximum cross-section in an upper region and a minimized cross-section in a lower region, with a gradual transition between the regions, is thus provided. The multi-well assembly of the present invention also improves the repeatability of positioning the filter plate and receiver plate in proper nesting relationship and provides stability during handling, mixing and shaking operations.

Abstract translation: 包括过滤板和接收板的多孔组件。 每个板包括多个孔，当过滤板与接收板放置成嵌套关系时，每个过滤板井具有相应的容纳板，井中延伸。 接收器板孔具有不均匀的横截面，以便当接收板和过滤板处于嵌套关系时，增加过滤板孔的外壁和对应的接收器板的内壁之间的间隙。 增加的间隙大小减少芯吸和交叉污染。 因此，提供了在上部区域中的最大横截面的多部分井和在下部区域中具有逐渐过渡的区域中的最小化横截面。 本发明的多孔组件还提高了将过滤板和接收板定位成适当的嵌套关系的重复性，并且在处理，混合和摇动操作期间提供了稳定性。

公开(公告)号：US09138742B2

公开(公告)日：2015-09-22

申请号：US14514853

申请日：2014-10-15

Applicant: EMD Millipore Corporation

Inventor： Christopher A. Scott ,  Brian Foley

IPC: B01L3/00

CPC classification number: B01L3/50255 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/0678 ,  B01L2200/0684 ,  B01L2200/141 ,  B01L2300/0681 ,  B01L2300/0829 ,  B01L2300/0858

Abstract: A multi-well assembly including a filter plate and receiver plate. Each plate includes a plurality of wells, which, when the filter plate is placed in nesting relationship with the receiver plate, each filter plate well has a corresponding receiver plate well into which it extends. The receiver plate wells are of a non-uniform cross-section in order to increase the gap between the outer walls of the filter plate wells and the inner walls of a corresponding receiver plate well when the receiver plate and filter plate are in nesting relationship. The increased gap size reduces wicking and cross-contamination. A multi-section well of maximum cross-section in an upper region and a minimized cross-section in a lower region, with a gradual transition between the regions, is thus provided. The multi-well assembly of the present invention also improves the repeatability of positioning the filter plate and receiver plate in proper nesting relationship and provides stability during handling, mixing and shaking operations.