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1.
公开(公告)号:US20200237920A1
公开(公告)日:2020-07-30
申请号:US16851779
申请日:2020-04-17
申请人: EVANGELOS KARAVAS , EFTHIMIOS KOUTRIS , DIMITRIOS BIKIARIS , SOTIRIA CHATIDOU , AMALIA DIAKIDOU , PANAGIOTIS BARMPALEXIS , LOUIZA KONSTANTI , KATERINA MINIOTI
发明人: EVANGELOS KARAVAS , EFTHIMIOS KOUTRIS , DIMITRIOS BIKIARIS , SOTIRIA CHATIDOU , AMALIA DIAKIDOU , PANAGIOTIS BARMPALEXIS , LOUIZA KONSTANTI , KATERINA MINIOTI
IPC分类号: A61K47/38 , A61K31/5377 , A61K9/00 , A61K9/70 , A61K31/675 , A61K47/14 , A61K47/34 , A61K47/44 , A61K47/46
摘要: The present invention relates to a controlled release sterile injectable formulation in the form of solution, suspension or sol-gel formulation for intramuscular or subcutaneous administration comprising a therapeutically effective amount of a neurokinin 1 receptor antagonist, in particular Aprepitant or Fosaprepitant or pharmaceutical acceptable salt, derivative or metabolite thereof. It also relates to a process for developing such formulations.