公开(公告)号：US11939308B2

公开(公告)日：2024-03-26

申请号：US17059754

申请日：2019-05-30

Applicant: EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION

Inventor： Kong Joo Lee ,  Hee-Yoon Lee ,  Je Jin Lee ,  Hwang Suk Kim ,  Ji-Wan Seo ,  Hongsoo Lee ,  Ji Soo Shin ,  Bo-kyung Kim

IPC: C07D303/18 ,  A23L33/10 ,  A61P35/04 ,  C07C35/21 ,  C07C43/23 ,  C07C235/56

CPC classification number: C07D303/18 ,  A23L33/10 ,  A61P35/04 ,  C07C35/21 ,  C07C43/23 ,  C07C235/56

Abstract: The present disclosure provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound or pharmaceutically acceptable salt thereof according to the present disclosure is a compound that increases Nm23-H1/NDPK activity and can inhibit cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.