公开(公告)号：US20210095247A1

公开(公告)日：2021-04-01

申请号：US17041050

申请日：2019-03-26

Applicant: EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION

Inventor： Saeyoung PARK ,  Sung Chul JUNG ,  Seo-ha MYUNG ,  Soo Yeon JUNG ,  Jiyeon KIM ,  Namhee JUNG ,  Yeonzi CHOI

IPC: C12N5/0793 ,  A61K35/30

Abstract: The present disclosure relates to a method for differentiating motor neurons from tonsil-derived mesenchymal stem cells, and a cell therapy agent using the same. The differentiation method of the present disclosure exhibits high differentiation potency into motor neurons, and thus enables a large quantity of motor neurons to be secured. Since the cells which are differentiated according to the present disclosure are obtained using discarded tonsillar tissues, there are fewer ethical issues. In addition, the cells are highly applicable as a cell therapy agent because they can be obtained easily in large quantities.