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公开(公告)号：US10047067B2
公开(公告)日：2018-08-14
申请号：US14424771
申请日：2013-08-02
Inventor： Yun Soo Bae , Hun Joo Ha , Kee In Lee , Kyung Hee Song
IPC: C07D401/04 , C07D413/14 , A61K31/4439 , A61K31/506 , C07D403/04 , C07D405/14
Abstract: The present invention provides a composition for preventing or treating kidney disease, the composition comprising a pyrazole derivative compound or a pharmaceutically acceptable salt thereof; and the composition of the present invention is effective in reducing proteinuria, reducing cell formation between glomerular blood vessels and suppressing kidney fibrosis.
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2.发明申请PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTION AND TREATMENT OF OSTEOPOROSIS CONTAINING SAME 审中-公开吡唑衍生物，其制备方法和组合物，用于预防和治疗含有其的卵磷脂公开(公告)号：US20140066404A1
公开(公告)日：2014-03-06
申请号：US14073601
申请日：2013-11-06
Inventor： Yun Soo Bae , Jee Hyun Lee , Mi Sun Seo , Soo Young Lee , Sun Choi , Kee In Lee , Hye Rin Bin , Do Min Lee
IPC: C07F7/08 , C07F5/02 , C07D405/14 , C07D401/04 , C07D403/04
CPC classification number: C07F7/0812 , C07D401/04 , C07D403/04 , C07D405/14 , C07F5/025
Abstract: The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.
Abstract translation: 本发明提供吡唑衍生物化合物及其药学上可接受的盐。 本发明的化合物具有优异的预防和治疗骨质疏松症的效果。
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3.发明申请COMPOSITION FOR PREVENTING OR TREATING KIDNEY DISEASE COMPRISING PYRAZOLE DERIVATIVE 审中-公开用于预防或治疗包含吡唑衍生物的药物疾病的组合物公开(公告)号：US20150218125A1
公开(公告)日：2015-08-06
申请号：US14424771
申请日：2013-08-02
Inventor： Yun Soo Bae , Hun Joo Ha , Kee In Lee , Kyung Hee Song
IPC: C07D401/04 , C07D403/04 , C07D405/14
CPC classification number: C07D401/04 , A61K31/4439 , A61K31/506 , C07D403/04 , C07D405/14 , C07D413/14
Abstract: The present invention provides a composition for preventing or treating kidney disease, the composition comprising a pyrazole derivative compound or a pharmaceutically acceptable salt thereof; and the composition of the present invention is effective in reducing proteinuria, reducing cell formation between glomerular blood vessels and suppressing kidney fibrosis.
Abstract translation: 本发明提供了用于预防或治疗肾病的组合物，该组合物包含吡唑衍生物化合物或其药学上可接受的盐; 本发明的组合物可有效减少蛋白尿，减少肾小球血管间的细胞形成并抑制肾纤维化。
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4.发明授权Pyrazole derivatives, preparation method thereof, and composition for prevention and treatment of osteoporosis containing same 有权吡唑衍生物，其制备方法和用于预防和治疗含有其的骨质疏松症的组合物公开(公告)号：US09000176B2
公开(公告)日：2015-04-07
申请号：US14073601
申请日：2013-11-06
Inventor： Yun Soo Bae , Jee Hyun Lee , Mi Sun Seo , Soo Young Lee , Sun Choi , Kee In Lee , Hye Rin Bin , Do Min Lee
IPC: A61K31/44 , C07D401/00 , C07F7/08 , C07D401/04 , C07D403/04 , C07D405/14 , C07F5/02
CPC classification number: C07F7/0812 , C07D401/04 , C07D403/04 , C07D405/14 , C07F5/025
Abstract: The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.
Abstract translation: 本发明提供吡唑衍生物化合物及其药学上可接受的盐。 本发明的化合物具有优异的预防和治疗骨质疏松症的效果。
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