公开(公告)号：US20220378750A1

公开(公告)日：2022-12-01

申请号：US17680782

申请日：2022-02-25

Applicant: EYEPOINT PHARMACEUTICALS, INC.

Inventor： Jeffrey Lyle Gray ,  Kande K.D. Amarasinghe ,  Cynthia Monesa Clark ,  Ryan Matthew Nichols ,  Matthew B. Maier

IPC: A61K31/426 ,  C07D277/64 ,  C07D277/28 ,  C07D417/04 ,  A61K31/427 ,  A61K31/428 ,  A61K31/497 ,  C07D277/60 ,  C07D277/30 ,  A61K9/00

Abstract: The present disclosure relates to compounds effective as human protein tyrosine phosphatase beta (HPTP-β) inhibitors thereby regulating angiogenesis. The present disclosure further relates to compositions comprising said human protein tyrosine phosphatase beta (HPTP-β) inhibitors, and to methods for regulating angiogenesis.